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Product Details
MA5-50087
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
7H7
Immunogen
Recombinant Human GLP1R protein
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% Proclin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Wet ice
RRID
AB_3093061
Target Information
Glucagon-like peptide-1(9-36)amide and GLP-1(9-37) are the forms of GLP-1 that result from the rapid degradation of the active forms of the peptide (GLP-1(7-36)amide and GLP-1(7-37)) by the enzyme dipeptidyl peptidase-IV (DPP-IV, also known as CD26 or adenosine deaminase binding protein). GLP-1 is a peptide hormone of the glucagon family, produced by the L cells of the intestinal mucosa from the same prohormone as glucagon. The active forms are potent stimulators of glucose-dependent insulin secretion. The sequence of GLP-1 is fully conserved in all mammalian species examined so far.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GLP-1 receptor; GLP-I receptor; GLP1 receptor; Glucagon-like peptide 1 receptor; glucagon-like peptide-1 receptor; seven transmembrane helix receptor
Gene Aliases: GLP-1; GLP-1-R; GLP-1R; GLP1R
UniProt ID: (Human) P43220
Entrez Gene ID: (Human) 2740
response to stress
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
positive regulation of cytosolic calcium ion concentration
learning or memory
regulation of heart contraction
cAMP-mediated signaling
positive regulation of blood pressure
regulation of insulin secretion
cellular response to glucagon stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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