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GLUT1 Antibody (MA5-37843) in ICC/IF
Immunofluorescence analysis of SLC2A1 was performed using 70% confluent log phase HEK 293 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.01% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with GLUT1 Recombinant Rabbit Monoclonal Antibody (ARC0304) (Product # MA5-37843) at 1:100 dilution in 0.1% BSA, incubated at 4 degrees celsius overnight, and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alex... View More
Product Details
MA5-37843
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
ARC0304
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 393-492 of human GLUT1/SLC2A1 (P11166)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2897763
Product Specific Information
Positive Samples: SH-SY5Y, K-562, Mouse brain
Immunogen sequence: ELFSQGPRPA AIAVAGFSNW TSNFIVGMCF QYVEQLCGPY VFIIFTVLLV LFFIFTYFKV PETKGRTFDE IASGFRQGGA SQSDKTPEEL FHPLGADSQV
Target Information
Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: choreoathetosis/spasticity, episodic (paroxysmal choreoathetosis/spasticity); glucose transporter glut1; Glucose transporter type 1, erythrocyte/brain; GLUT-1; GT1; HepG2 glucose transporter; human T-cell leukemia virus (I and II) receptor; MGC141895; MGC141896; receptor for HTLV-1 and HTLV-2; solute carrier family 2 (facilitated glucose transporter), member 1; Solute carrier family 2, facilitated glucose transporter member 1; solute carrier family 2, member 1
Gene Aliases: CSE; DYT17; DYT18; DYT9; EIG12; GLUT; GLUT-1; GLUT1; GLUT1DS; HTLVR; PED; SDCHCN; SLC2A1
UniProt ID: (Human) P11166, (Mouse) P17809
Entrez Gene ID: (Human) 6513, (Mouse) 20525
glucose transmembrane transporter activity
protein binding
kinase binding
dehydroascorbic acid transporter activity
identical protein binding
xenobiotic transporter activity
protein self-association
D-glucose transmembrane transporter activity
transporter activity
sugar:proton symporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
protein complex assembly
transport
carbohydrate transport
glucose transport
proton transport
hexose transmembrane transport
cellular response to glucose starvation
xenobiotic transport
glucose import
transmembrane transport
dehydroascorbic acid transport
cation transmembrane transport
lactose biosynthetic process
response to osmotic stress
L-ascorbic acid metabolic process
regulation of insulin secretion
glucose transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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