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Product Details
BS-3689R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GM-CSFR Beta, amino acids 441-540.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta c; beta common cytokine receptor; CD antigen CD131; CD131; CD131 antigen; CDw131; colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage); colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); Colony-stimulating factor 2 receptor subunit beta-2; colony-stimulating factor-2 receptor, beta, low-affinity; common beta chain; Cytokine receptor common subunit beta; GM-CSF/IL-3/IL-5 receptor common beta subunit; GM-CSF/IL-3/IL-5 receptor common beta-chain; IL-3 RB; IL-3 Receptor beta; IL-3 receptor class 2 subunit beta; IL-3R class 2 subunit beta; IL3R beta; interleukin 3 common beta chain; interleukin 3 receptor/granulocyte-macrophage colony stimulating factor 3 receptor, beta (high affinity); Interleukin-3 receptor class 2 subunit beta; Interleukin-3 receptor class II beta chain
Gene Aliases: Ai2ca; AI848964; AIC2A; AIC2B; Bc; BetaIl3; Bil3; CD131; CDw131; CSF2RB; Csf2rb1; Csf2rb2; Csfgmrb; Il3r; IL3RB; Il3rb1; Il3rb2; IL5RB; SMDP5
UniProt ID: (Human) P32927, (Mouse) P26955, (Mouse) P26954
Entrez Gene ID: (Human) 1439, (Rat) 171081, (Mouse) 12983, (Mouse) 12984
MAPK cascade
signal transduction
respiratory gaseous exchange
peptidyl-tyrosine phosphorylation
cellular response to interleukin-3
interleukin-5-mediated signaling pathway
interleukin-3-mediated signaling pathway
positive regulation of GTPase activity
cellular protein metabolic process
cytokine-mediated signaling pathway
response to lipopolysaccharide
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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