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This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GMP reductase 1; GMPR 1; guanine monophosphate reductase; Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1
Gene Aliases: 2310004P21Rik; AV028449; GMPR; GMPR 1; GMPR1
UniProt ID: (Human) P36959, (Mouse) Q9DCZ1, (Rat) Q9Z244
Entrez Gene ID: (Human) 2766, (Mouse) 66355, (Rat) 117533
Molecular Function:
reductase
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