Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MRLVILDNY DLASEWAAKY ICNRIIQFKP GQDRYFTLGL PTGSTPLGCY KKLIEYHKNG HLSFKYVKTF NMDEYVGLPR NHPESYHSYM WNNFFKHIDI DPNNAHILDG NAADLQAECD AFENKIKEAG GIDLFVGGIG PDGHIAFNEP GSSLVSRTRL KTLAMDTILA NAKYFDGDLS KVSTMALTVG VGTVMDAREV MILITGAHKA FALYKAIEGV NHMWTVSAFQ QHPRTIFVCD EDATLELRVK TVKYFKGLMH VHNKLVDPLF SMKDGN (1-275 aa encoded by B C015532)
GNPDA2 (Glucosamine-6-phosphate deaminase) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glcN6P deaminase 2; Glucosamine-6-phosphate deaminase 2; Glucosamine-6-phosphate isomerase 2; Glucosamine-6-phosphate isomerase SB52; GNPDA 2; oscillin
Gene Aliases: 4921523I18Rik; 4933412A11Rik; BB189630; GNP2; GNPDA; GNPDA2; Kiaa4008; mKIAA4008; SB52
UniProt ID: (Human) Q8TDQ7, (Mouse) Q9CRC9
Entrez Gene ID: (Human) 132789, (Mouse) 67980, (Rat) 289608
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