Product References
Role of asparagine biosynthesis pathway in Siniperca chuatsi rhabdovirus proliferation.
Frontiers in microbiology
Li F,Fu X,Luo X,Lin Q,Liang H,Niu Y,Liu L,Li N
Tue Apr 18 00:00:00 EDT 2023
ASS1-Mediated Reductive Carboxylation of Cytosolic Glutamine Confers Ferroptosis Resistance in Cancer Cells.
Cancer research
Hu Q,Dai J,Zhang Z,Yu H,Zhang J,Zhu X,Qin Y,Zhang L,Zhang P
Mon May 15 00:00:00 EDT 2023
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy.
EMBO molecular medicine
Southwell N,Primiano G,Nadkarni V,Attarwala N,Beattie E,Miller D,Alam S,Liparulo I,Shurubor YI,Valentino ML,Carelli V,Servidei S,Gross SS,Manfredi G,Chen Q,D'Aurelio M
Mon Jul 10 00:00:00 EDT 2023
Mitochondrial redox adaptations enable alternative aspartate synthesis in SDH-deficient cells.
eLife
Hart ML,Quon E,Vigil ABG,Engstrom IA,Newsom OJ,Davidsen K,Hoellerbauer P,Carlisle SM,Sullivan LB
Wed Mar 08 00:00:00 EST 2023
Gaseous signal molecule SO2 regulates autophagy through PI3K/AKT pathway inhibits cardiomyocyte apoptosis and improves myocardial fibrosis in rats with type II diabetes.
The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology
Zhao J,Wu Q,Yang T,Nie L,Liu S,Zhou J,Chen J,Jiang Z,Xiao T,Yang J,Chu C
Tue Nov 01 00:00:00 EDT 2022
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H2S oxidation.
The Journal of biological chemistry
Kumar R,Landry AP,Guha A,Vitvitsky V,Lee HJ,Seike K,Reddy P,Lyssiotis CA,Banerjee R
Sat Jan 01 00:00:00 EST 2022
NFYA promotes the anti-tumor effects of gluconeogenesis in hepatocellular carcinoma through the regulation of PCK1 expression.
Frontiers in cell and developmental biology
Tsujimoto G,Ito R,Yoshikawa K,Ueki C,Okada N
Tue Sep 13 00:00:00 EDT 2022
Neddylation inhibition induces glutamine uptake and metabolism by targeting CRL3SPOP E3 ligase in cancer cells.
Nature communications
Zhou Q,Lin W,Wang C,Sun F,Ju S,Chen Q,Wang Y,Chen Y,Li H,Wang L,Hu Z,Jin H,Wang X,Sun Y
Tue May 31 00:00:00 EDT 2022
Identification and Validation of a Nine-Gene Amino Acid Metabolism-Related Risk Signature in HCC.
Frontiers in cell and developmental biology
Zhao Y,Zhang J,Wang S,Jiang Q,Xu K
Sat Sep 25 00:00:00 EDT 2021
The mitochondrial NADH pool is involved in hydrogen sulfide signaling and stimulation of aerobic glycolysis.
The Journal of biological chemistry
Vitvitsky V,Kumar R,Libiad M,Maebius A,Landry AP,Banerjee R
Tue Aug 31 00:00:00 EDT 2021
Hepatic mTORC1 signaling activates ATF4 as part of its metabolic response to feeding and insulin.
Molecular metabolism
Byles V,Cormerais Y,Kalafut K,Barrera V,Hughes Hallett JE,Sui SH,Asara JM,Adams CM,Hoxhaj G,Ben-Sahra I,Manning BD
Mon Nov 01 00:00:00 EDT 2021
Aspartate availability limits hematopoietic stem cell function during hematopoietic regeneration.
Cell stem cell
Qi L,Martin-Sandoval MS,Merchant S,Gu W,Eckhardt M,Mathews TP,Zhao Z,Agathocleous M,Morrison SJ
Thu Nov 04 00:00:00 EDT 2021
Endogenous glutamate determines ferroptosis sensitivity via ADCY10-dependent YAP suppression in lung adenocarcinoma.
Theranostics
Zhang X,Yu K,Ma L,Qian Z,Tian X,Miao Y,Niu Y,Xu X,Guo S,Yang Y,Wang Z,Xue X,Gu C,Fang W,Sun J,Yu Y,Wang J
Thu Jul 29 00:00:00 EDT 2021
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Cell metabolism
Wang YP,Sharda A,Xu SN,van Gastel N,Man CH,Choi U,Leong WZ,Li X,Scadden DT
Tue May 04 00:00:00 EDT 2021
Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis.
Cell metabolism
Wang YP,Sharda A,Xu SN,van Gastel N,Man CH,Choi U,Leong WZ,Li X,Scadden DT
Tue May 04 00:00:00 EDT 2021
USP29 coordinates MYC and HIF1α stabilization to promote tumor metabolism and progression.
Oncogene
Tu R,Kang W,Yang M,Wang L,Bao Q,Chen Z,Dong Y,Wang J,Jiang J,Liu H,Qing G
Mon Nov 01 00:00:00 EDT 2021
Inhibiting both proline biosynthesis and lipogenesis synergistically suppresses tumor growth.
The Journal of experimental medicine
Liu M,Wang Y,Yang C,Ruan Y,Bai C,Chu Q,Cui Y,Chen C,Ying G,Li B
Mon Mar 02 00:00:00 EST 2020
Ischemic Neuroprotectant PKCε Restores Mitochondrial Glutamate Oxaloacetate Transaminase in the Neuronal NADH Shuttle after Ischemic Injury.
Translational stroke research
Xu J,Khoury N,Jackson CW,Escobar I,Stegelmann SD,Dave KR,Perez-Pinzon MA
Mon Jun 01 00:00:00 EDT 2020
Glutamine Metabolism Is Required for Collagen Protein Synthesis in Lung Fibroblasts.
American journal of respiratory cell and molecular biology
Hamanaka RB,O'Leary EM,Witt LJ,Tian Y,Gökalp GA,Meliton AY,Dulin NO,Mutlu GM
Fri Nov 01 00:00:00 EDT 2019
Preventing BRCA1/ZBRK1 repressor complex binding to the GOT2 promoter results in accelerated aspartate biosynthesis and promotion of cell proliferation.
Molecular oncology
Hong R,Zhang W,Xia X,Zhang K,Wang Y,Wu M,Fan J,Li J,Xia W,Xu F,Chen J,Wang S,Zhan Q
Mon Apr 01 00:00:00 EDT 2019
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cell research
Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC
Wed Aug 01 00:00:00 EDT 2018
Glutaminase GLS1 senses glutamine availability in a non-enzymatic manner triggering mitochondrial fusion.
Cell research
Cai WF,Zhang C,Wu YQ,Zhuang G,Ye Z,Zhang CS,Lin SC
Wed Aug 01 00:00:00 EDT 2018
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Nature communications
Wang YQ,Wang HL,Xu J,Tan J,Fu LN,Wang JL,Zou TH,Sun DF,Gao QY,Chen YX,Fang JY
Wed Feb 07 00:00:00 EST 2018
Sirtuin5 contributes to colorectal carcinogenesis by enhancing glutaminolysis in a deglutarylation-dependent manner.
Nature communications
Wang YQ,Wang HL,Xu J,Tan J,Fu LN,Wang JL,Zou TH,Sun DF,Gao QY,Chen YX,Fang JY
Wed Feb 07 00:00:00 EST 2018
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nature communications
Feist M,Schwarzfischer P,Heinrich P,Sun X,Kemper J,von Bonin F,Perez-Rubio P,Taruttis F,Rehberg T,Dettmer K,Gronwald W,Reinders J,Engelmann JC,Dudek J,Klapper W,Trümper L,Spang R,Oefner PJ,Kube D
Tue Apr 17 00:00:00 EDT 2018
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nature communications
Feist M,Schwarzfischer P,Heinrich P,Sun X,Kemper J,von Bonin F,Perez-Rubio P,Taruttis F,Rehberg T,Dettmer K,Gronwald W,Reinders J,Engelmann JC,Dudek J,Klapper W,Trümper L,Spang R,Oefner PJ,Kube D
Tue Apr 17 00:00:00 EDT 2018
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nature communications
Feist M,Schwarzfischer P,Heinrich P,Sun X,Kemper J,von Bonin F,Perez-Rubio P,Taruttis F,Rehberg T,Dettmer K,Gronwald W,Reinders J,Engelmann JC,Dudek J,Klapper W,Trümper L,Spang R,Oefner PJ,Kube D
Tue Apr 17 00:00:00 EDT 2018
Cooperative STAT/NF-κB signaling regulates lymphoma metabolic reprogramming and aberrant GOT2 expression.
Nature communications
Feist M,Schwarzfischer P,Heinrich P,Sun X,Kemper J,von Bonin F,Perez-Rubio P,Taruttis F,Rehberg T,Dettmer K,Gronwald W,Reinders J,Engelmann JC,Dudek J,Klapper W,Trümper L,Spang R,Oefner PJ,Kube D
Tue Apr 17 00:00:00 EDT 2018
Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations.
Cell metabolism
Chen Q,Kirk K,Shurubor YI,Zhao D,Arreguin AJ,Shahi I,Valsecchi F,Primiano G,Calder EL,Carelli V,Denton TT,Beal MF,Gross SS,Manfredi G,D'Aurelio M
Tue May 01 00:00:00 EDT 2018
HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine
Li W,Chen C,Zhao X,Ye H,Zhao Y,Fu Z,Pan W,Zheng S,Wei L,Nong T,Li Z,Chen R
Wed Nov 01 00:00:00 EDT 2017
HIF-2α regulates non-canonical glutamine metabolism via activation of PI3K/mTORC2 pathway in human pancreatic ductal adenocarcinoma.
Journal of cellular and molecular medicine
Li W,Chen C,Zhao X,Ye H,Zhao Y,Fu Z,Pan W,Zheng S,Wei L,Nong T,Li Z,Chen R
Wed Nov 01 00:00:00 EDT 2017
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation.
Nature communications
Tan HWS,Sim AYL,Long YC
Thu Aug 24 00:00:00 EDT 2017
Glutamine metabolism regulates autophagy-dependent mTORC1 reactivation during amino acid starvation.
Nature communications
Tan HWS,Sim AYL,Long YC
Thu Aug 24 00:00:00 EDT 2017
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Oncotarget
Kitazawa S,Ebara S,Ando A,Baba Y,Satomi Y,Soga T,Hara T
Tue Apr 25 00:00:00 EDT 2017
Succinate dehydrogenase B-deficient cancer cells are highly sensitive to bromodomain and extra-terminal inhibitors.
Oncotarget
Kitazawa S,Ebara S,Ando A,Baba Y,Satomi Y,Soga T,Hara T
Tue Apr 25 00:00:00 EDT 2017
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 EDT 2016
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 EDT 2016
Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients.
Journal of proteome research
Qin S,Zhou Y,Gray L,Kusebauch U,McEvoy L,Antoine DJ,Hampson L,Park KB,Campbell D,Caballero J,Glusman G,Yan X,Kim TK,Yuan Y,Wang K,Rowen L,Moritz RL,Omenn GS,Pirmohamed M,Hood L
Fri Oct 07 00:00:00 EDT 2016
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 EDT 2015
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions.
Cell research
Sun L,Song L,Wan Q,Wu G,Li X,Wang Y,Wang J,Liu Z,Zhong X,He X,Shen S,Pan X,Li A,Wang Y,Gao P,Tang H,Zhang H
Wed Apr 01 00:00:00 EDT 2015