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Product Details
PA5-121045
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 30-200 of human GOT2 (NP_002071.2).
Conjugate
Form
Liquid
Concentration
3.72 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2914617
Product Specific Information
Positive test controls include: SW620, HepG2, BT-474, Jurkat, Mouse kidney, Mouse liver, Mouse brain, Rat kidney, Rat brain. The target is usually found in the following locations: Cell membrane, Mitochondrion matrix.
Immunogen sequence: SSWWTHVEMG PPDPILGVTE AFKRDTNSKK MNLGVGAYRD DNGKPYVLPS VRKAEAQIAA KNLDKEYLPI GGLAEFCKAS AELALGENSE VLKSGRFVTV QTISGTGALR IGASFLQRFF KFSRDVFLPK PTWGNHTPIF RDAGMQLQGY RYYDPKTCGF DFTGAVEDIS K
Target Information
GOT2 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aspartate aminotransferase 2; Aspartate aminotransferase, mitochondrial; aspartate transaminase 2; FABP-1; FABPpm; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; glutamate oxaloacetate transaminase 2, mitochondrial; Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2); glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; mAspAT; mitochondrial aspartate aminotransferase; plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A
Gene Aliases: AL022787; ASPATA; FABP-pm; Got-2; GOT2; KAT4; KATIV; KYAT4; Maat; mAspAT; mitAAT
UniProt ID: (Human) P00505, (Mouse) P05202, (Rat) P00507
Entrez Gene ID: (Human) 2806, (Mouse) 14719, (Rat) 25721
L-aspartate:2-oxoglutarate aminotransferase activity
phospholipid binding
kynurenine-oxoglutarate transaminase activity
amino acid binding
enzyme binding
pyridoxal phosphate binding
identical protein binding
protein homodimerization activity
poly(A) RNA binding
L-phenylalanine:2-oxoglutarate aminotransferase activity
catalytic activity
transaminase activity
transferase activity
carboxylic acid binding
transaminase
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
cellular amino acid biosynthetic process
fatty acid transport
4-hydroxyproline catabolic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
response to ethanol
L-kynurenine metabolic process
cellular amino acid metabolic process
transport
lipid transport
biosynthetic process
dicarboxylic acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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