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Invitrogen
GOT2 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Independent antibody to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 9
GOT2 Antibody (PA5-27572) in IHC (P)
GOT2 Polyclonal Antibody detects GOT2 protein at cytoplasm in mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. GOT2 Polyclonal Antibody (Product # PA5-27572) diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min.
Product Details
PA5-27572
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 174 and 392 of Human GOT2
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2545048
Product Specific Information
Recommended positive controls: 293T, HepG2, Neuro2A, rat lung.
Predicted reactivity: Mouse (92%), Rat (92%), Xenopus laevis (81%), Dog (92%), Pig (89%), Chicken (82%), Bovine (90%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
GOT2 is a glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aspartate aminotransferase 2; Aspartate aminotransferase, mitochondrial; aspartate transaminase 2; FABP-1; FABPpm; Fatty acid-binding protein; FLJ40994; Glutamate oxaloacetate transaminase 2; glutamate oxaloacetate transaminase 2, mitochondrial; Glutamate oxaloacetate transaminase 2, mitochondrial (aspartate aminotransferase 2); glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2); Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; mAspAT; mitochondrial aspartate aminotransferase; plasma membrane fatty acid binding protein; Plasma membrane-associated fatty acid-binding protein; Transaminase A
Gene Aliases: AL022787; ASPATA; FABP-pm; Got-2; GOT2; KAT4; KATIV; KYAT4; Maat; mAspAT; mitAAT
UniProt ID: (Human) P00505, (Mouse) P05202, (Rat) P00507
Entrez Gene ID: (Human) 2806, (Mouse) 14719, (Rat) 25721
L-aspartate:2-oxoglutarate aminotransferase activity
phospholipid binding
kynurenine-oxoglutarate transaminase activity
amino acid binding
enzyme binding
pyridoxal phosphate binding
identical protein binding
protein homodimerization activity
poly(A) RNA binding
L-phenylalanine:2-oxoglutarate aminotransferase activity
catalytic activity
transaminase activity
transferase activity
carboxylic acid binding
transaminase
gluconeogenesis
2-oxoglutarate metabolic process
oxaloacetate metabolic process
aspartate metabolic process
aspartate biosynthetic process
aspartate catabolic process
glutamate metabolic process
cellular amino acid biosynthetic process
fatty acid transport
4-hydroxyproline catabolic process
glutamate catabolic process to aspartate
glutamate catabolic process to 2-oxoglutarate
response to ethanol
L-kynurenine metabolic process
cellular amino acid metabolic process
transport
lipid transport
biosynthetic process
dicarboxylic acid metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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