Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: SK-N-SH.
Predicted reactivity: Human (99%), Mouse (93%), Rat (92%), Zebrafish (86%), Xenopus laevis (85%), Rhesus Monkey (99%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: glycerol-3-phosphate dehydrogenase 2 (mitochondrial); Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitohondrial glycerophosphate dehydrogenase gene; mtGPD; testicular tissue protein Li 76
Gene Aliases: GDH2; GPD2; GPDM; mGPDH
UniProt ID: (Human) P43304
Entrez Gene ID: (Human) 2820
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