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Product Details
BS-16293R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human GPR172A, amino acids 101-200.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.03% ProClin 300
Storage conditions
-20°C
Shipping conditions
Wet ice
Target Information
This gene encodes a membrane protein which belongs to the riboflavin transporter family. In humans, riboflavin must be obtained by intestinal absorption because it cannot be synthesized by the body. The water-soluble vitamin riboflavin is processed to the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) which then act as intermediaries in many cellular metabolic reactions. Paralogous members of the riboflavin transporter gene family are located on chromosomes 17 and 20. Unlike other members of this family, this gene has higher expression in brain tissue than small intestine. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. Mutations in this gene have been associated with Brown-Vialetto-Van Laere syndrome 2 - an autosomal recessive progressive neurologic disorder characterized by deafness, bulbar dysfunction, and axial and limb hypotonia. [provided by RefSeq, Jul 2012].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G protein-coupled receptor 172A; G protein-coupled receptor 172B; hRFT3; mRFT1; PERV-A receptor 1; PERV-A receptor 2 homolog; PEVR1; Porcine endogenous retrovirus A receptor 1; Porcine endogenous retrovirus A receptor 2; Porcine endogenous retrovirus A receptor 2 homolog; Protein GPR172A; Protein GPR172B; putative G-protein coupled receptor GPCR41; Riboflavin transporter 1; Riboflavin transporter 3; rRFT1; solute carrier family 52 (riboflavin transporter), member 2; Solute carrier family 52, riboflavin transporter, member 2
Gene Aliases: 2010003P03Rik; BVVLS2; D15Ertd747e; GPCR41; GPCR42; GPR172A; Gpr172b; hRFT3; mRFT1; PAR1; PAR2; Rft1; RFT3; RFVT2; RGD1560410; rRFT1; SLC52A2
UniProt ID: (Human) Q9HAB3, (Mouse) Q9D8F3, (Rat) B5MEV3
Entrez Gene ID: (Human) 79581, (Mouse) 52710, (Rat) 362942
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