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Invitrogen
GPX4 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 1
GPX4 Antibody (PA5-84385)
Relative expression in different tissues in IHC: Detection of differential expression levels of GPX4 demonstrates antibody specificity. Immunohistochemical analysis of GPX4 using anti-GPX4 Polyclonal Antibody (Product #PA5-84385), shows significant staining of GPX4 in testis and shows minimal or weak staining in pancreas tissues. The relative expression levels of GPX4 within each tissue is shown using RNA-... View More
Product Details
PA5-84385
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GPX4. Recombinant protein control fragment (Product #RP-106868).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2791537
Product Specific Information
Immunogen sequence: TMCASRDDWR CARSMHEFSA KDIDGHMVNL DKYRGFVCIV TNVAS
Target Information
Glutathione peroxidase catalyzes the reduction of hydrogen peroxide, organic hydroperoxide, and lipid peroxides by reduced glutathione and functions in the protection of cells against oxidative damage. Human plasma glutathione peroxidase has been shown to be a selenium-containing enzyme and the UGA codon is translated into a selenocysteine. Through alternative splicing and transcription initiation, rat produces proteins that localize to the nucleus, mitochondrion, and cytoplasm. In humans, experimental evidence for alternative splicing exists; alternative transcription initiation and the cleavage sites of the mitochondrial and nuclear transit peptides need to be experimentally verified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Glutathione peroxidase 4; GPx-4; HGNC:4556; PHGPx; phospholipid hydroperoxidase; Phospholipid hydroperoxide glutathione peroxidase GPX4; sperm nucleus glutathione peroxidase
Gene Aliases: GPx-4; GPX4; GSHPx-4; MCSP; PHGPx; SMDS; snGPx; snPHGPx
UniProt ID: (Human) P36969
Entrez Gene ID: (Human) 2879
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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