Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: MADLEAVLA DVSYLMAMEK SKATPAARAS KRIVLPEPSI RSVMQKYLAE RNEITFDKIF NQKIGFLLFK DFCLNEINEA VPQVKFYEEI KEYEKLDNEE DRLCRSRQIY DAYIMKELLS CSHPFSKQAV EHVQSHLSKK QVTSTLFQPY IEEICESLRG DIFQKFMESD KFTRFCQWKN VELNIHLTMN EFSVHRIIGR GGFGEVYGCR KADTGKMYAM KCLDKKRIKM KQGETLALNE RIMLSLVSTG DCPFIVCMTY AFHTPDKLCF ILDLMNGGDL HYHLSQHGVF SEKEMRFYAT EIILGLEHMH NRFVVYRDLK PANILLDEHG HARISDLGLA CDFSKKKPHA SVGTHGYMAP EVLQKGTAYD SSADWFSLGC MLFKLLRG (1-387 aa encoded by BC036797)
ADRBK2, or adrenergic beta receptor kinase 2 is a serine/threonine kinase that is thought to act as a regulator of receptor function. Overall, the ADRBK2 enzyme, also known as GRK3, has 85% amino acid similarity with ADRBK1, with the protein kinase catalytic domain having 95% similarity. The ADRBK2 mRNA is approximately 8 kilobases with a distribution similar to that of ADRBK1. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: adrenergic receptor kinase, beta 2 (G-protein-linked receptor kinase); adrenergic, beta, receptor kinase 2; beta ARK2; Beta-adrenergic receptor kinase 2; Beta-ARK-2; G protein-coupled receptor kinase 3; G-protein-coupled receptor kinase 3
Gene Aliases: 4833444A01Rik; Adrbk-2; ADRBK2; AI851927; AW551196; Bark-2; BARK2; GRK3
UniProt ID: (Mouse) Q3UYH7, (Rat) P26819, (Human) P35626
Entrez Gene ID: (Mouse) 320129, (Rat) 25372, (Human) 157
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