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Search Thermo Fisher Scientific
Immunogen sequence: LGCLIYEMIE GQSPFRGRKE KVKREEVDRR VLETEEVYSH KFSEEAKSIC KMLLTKDAKQ RLGCQEEGAA EVKRHPFFRN MNFKRLEAGM LDPPFVPDPR AVYCKDVLDI EQFSTVKGVN LDHTDDDFYS KFSTGSVSIP WQNEMIETEC FKELNVFGPN GTLPPDLNRN HPPEPPKKGL LQRLFKRQHQ NNSKSSPSSK TSFNHHINSN HVSSNSTGSS; Positive Samples: A-549, U-251MG, HepG2, 293T, HT-1080, Mouse liver, Mouse lung; Cellular Location: Cell membrane, Cytoplasm, Nucleus, Peripheral membrane protein
GRK5 is a serine/threonine kinase that regulates the activity of a variety of G protein-coupled receptors and the motility of polymorphonuclear leukocytes. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Alpha-CP4; FP2025; G protein-coupled receptor kinase 5; G protein-coupled receptor kinase GRK5; GRK; GRK-pan; Pan-GRK; Poly(rC)-binding protein 4
Gene Aliases: 1200003L19Rik; AlphaCP-4; GPRK5; GRK5; Pcbp4
UniProt ID: (Human) P34947, (Mouse) Q8VEB1, (Rat) Q62833, (Mouse) P57724
Entrez Gene ID: (Human) 2869, (Mouse) 14773, (Rat) 59075, (Mouse) 59092
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