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Product Details
PA5-61182
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GRTP1. Recombinant protein control fragment (Product #RP-97976).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642228
Product Specific Information
Immunogen sequence: VALTLIKQHQ ELILEATSVP DICDKFKQIT KGSFVMECHT FMQKIFSEPG SLSMATVAKL RESCR
Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 89%.
Target Information
GRTP1, also known as germ cell-specific gene 1-related protein, is a protein that is expressed in the testis and is involved in the regulation of spermatogenesis, the process of sperm cell development. It is a member of the GRP family of proteins, which are characterized by a conserved motif called the GRP domain. GRTP1 is thought to play a role in the differentiation of spermatogonia into spermatocytes and in the regulation of meiosis, the process of cell division that produces haploid cells. Mutations in the GRTP1 gene have been associated with male infertility. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Growth hormone-regulated TBC protein 1; RP11-391H12.7; TBC1 domain family member 6
Gene Aliases: GRTP1; TBC1D6
UniProt ID: (Human) Q5TC63
Entrez Gene ID: (Human) 79774
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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