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Product Details
H00002950-M03
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
3E6-H2
Immunogen
GSTP1 (AAH10915, 1 a.a. approximately 210 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: MPPYTVVYFP VRGRCAALRM LLADQGQSWK EEVVTVETWQ EGSLKASCLY GQLPEFQDGD LTLYQSNTIL RHLGRTLGLY GKDQQEAALV DMVNDGVEDL RCKYVSLIYT NYEAGKDDYV KALPGQLKPF ETLLSQNQGG KTFIVGDQIS FADYNLLDLL LIHEVLAPGC LDAFPLLSAY VGRLSARPKL KAFLASPEYV NLPINGNGKQ
Target Information
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; Glutathione S-transferase P; GST class-pi; GSTP1-1; HGNC:4638
Gene Aliases: DFN7; FAEES3; GST3; GSTP; GSTP1; HEL-S-22; PI
UniProt ID: (Human) P09211
Entrez Gene ID: (Human) 2950
response to reactive oxygen species
negative regulation of acute inflammatory response
negative regulation of protein kinase activity
glutathione metabolic process
xenobiotic metabolic process
central nervous system development
negative regulation of biosynthetic process
negative regulation of tumor necrosis factor-mediated signaling pathway
oligodendrocyte development
organ regeneration
response to estradiol
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
cellular response to insulin stimulus
regulation of stress-activated MAPK cascade
negative regulation of stress-activated MAPK cascade
positive regulation of superoxide anion generation
response to L-ascorbic acid
common myeloid progenitor cell proliferation
nitric oxide storage
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
negative regulation of JUN kinase activity
linoleic acid metabolic process
response to ethanol
response to mercury ion
negative regulation of fibroblast proliferation
negative regulation of nitric-oxide synthase biosynthetic process
regulation of ERK1 and ERK2 cascade
negative regulation of ERK1 and ERK2 cascade
negative regulation of leukocyte proliferation
cellular response to lipopolysaccharide
cellular response to epidermal growth factor stimulus
cellular response to glucocorticoid stimulus
cellular response to cell-matrix adhesion
negative regulation of monocyte chemotactic protein-1 production
cellular oxidant detoxification
glutathione derivative biosynthetic process
negative regulation of extrinsic apoptotic signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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