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Product Details
PA5-52122
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GTF2H3. Recombinant protein control fragment (Product #RP-102495).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2642257
Product Specific Information
Immunogen sequence: LNLLVIVVDA NPIWWGKQAL KESQFTLSKC IDAVMVLGNS HLFMNRSNKL AVIASHIQES RFLYPGKNGR LGDFFGDPGN PPEFNPSGSK DGKYELLTSA NEVIVEEIKD LMTKSDIKGQ HTETLLAG
Highest antigen sequence identity to the following orthologs: Mouse - 90%, Rat - 91%.
Target Information
GTF2H3 interacts with HIV-1 Tat as a component of the HIV-1 transcription pre-initiation complex, but is released from the elongation complex which includes P-TEFb. It synergizes with HIV-1 Tat to induce transcription elongation from the HIV-1 LTR promoter.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Basic transcription factor 2 34 kDa subunit; BTF2 p34; General transcription factor IIH polypeptide 3; General transcription factor IIH subunit 3; general transcription factor IIH, polypeptide 3, 34kDa; TFIIH basal transcription factor complex p34 subunit
Gene Aliases: BTF2; GTF2H3; P34; TFB4; TFIIH
UniProt ID: (Human) Q13889
Entrez Gene ID: (Human) 2967
damaged DNA binding
transcription factor activity, sequence-specific DNA binding
protein kinase activity
protein binding
DNA-dependent ATPase activity
translation factor activity, RNA binding
RNA polymerase II carboxy-terminal domain kinase activity
metal ion binding
protein N-terminus binding
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
nucleotide-excision repair, DNA duplex unwinding
DNA repair
transcription-coupled nucleotide-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
transcription initiation from RNA polymerase I promoter
transcription elongation from RNA polymerase I promoter
termination of RNA polymerase I transcription
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
7-methylguanosine mRNA capping
translation
nucleotide-excision repair, DNA incision
phosphorylation of RNA polymerase II C-terminal domain
global genome nucleotide-excision repair
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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