Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
H00002969-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GTF2I (AAH99907.1, 1 a.a. approximately 976 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Cell lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MAQVAMSTLP VEDEESSESR MVVTFLMSAL ESMCKELAKS KAEVACIAVY ETDVFVVGTE RGRAFVNTRK DFQKDFVKYC VEEEEKAAEM HKMKSTTQAN RMSVDAVEIE TLRKTVEDYF CFCYGKALGK STVVPVPYEK MLRDQSAVVV QGLPEGVAFK HPENYDLATL KWILENKAGI SFIIKRPFLE PKKHVGGRVM VTDADRSILS PGGSCGPIKV KTEPTEDSGI SLEMAAVTVK EESEDPDYYQ YNIQGPSETD DVDEKQPLSK PLQGSHHSSE GNEGTEMEVP AEDDDYSPPS KRPKANELPQ PPVPEPANAG KRKVREFNFE KWNARITDLR KQVEELFERK YAQAIKAKGP VTIPYPLFQS HVEDLYVEGL PEGIPFRRPS TYGIPRLERI LLAKERIRFV IKKHELLNST REDLQLDKPA SGVKEEWYAR ITKLRKMVDQ LFCKKFAEAL GSTEAKAVPY QKFEAHPNDL YVEGLPENIP FRSPSWYGIP RLEKIIQVGN RIKFVIKRPE LLTHSTTEVT QPRTNTPVKE DWNVRITKLR KQVEEIFNLK FAQALGLTEA VKVPYPVFES NPEFLYVEGL PEGIPFRSPT WFGIPRLERI VRGSNKIKFV VKKPELVISY LPPGMASKIN TKALQSPKRP RSPGSNSKVP EIEVTVEGPN NNNPQTSAVR TPTQTNGSNV PFKPRGREFS FEAWNAKITD LKQKVENLFN EKCGEALGLK QAVKVPFALF ESFPEDFYVE GLPEGVPFRR PSTFGIPRLE KILRNKAKIK FIIKKPEMFE TAIKESTSSK SPPRKINSSP NVNTTASGVE DLNIIQVTIP DDDNERLSKV EKARQLREQV NDLFSRKFGE AIGMGFPVKV PYRKITINRG CVVVDGMPPG VSFKAPSYLE ISSMRRILDS AEFIKFTVIR PFPGLVVNNQ LVDQSESEGP VIQESAEPSQ LEVPATEEIK ETDGSSQIKQ EPDPTW
Target Information
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: BAP-135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTFII-I; OTTHUMP00000209509; SPIN; SRF-Phox1-interacting protein; tfiii; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
Gene Aliases: 6030441I21Rik; BAP-135; BAP135; BTKAP1; DIWS; Diws1t; GTF2I; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
UniProt ID: (Human) P78347, (Mouse) Q9ESZ8
Entrez Gene ID: (Human) 2969, (Mouse) 14886
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
transition between slow and fast fiber
negative regulation of angiogenesis
negative regulation of cytosolic calcium ion concentration
transcription, DNA-templated
regulation of transcription, DNA-templated
embryo development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support