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Product Details
H00002969-M02
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2D6
Immunogen
GTF2I (AAH04472.1, 36 a.a. approximately 274 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: ELAKSKAEVA CIAVYETDVF VVGTERGRAF VNTRKDFQKD FVKYCVEEEE KAAEMHKMKS TTQANRMSVD AVEIETLRKT VEDYFCFCYG KALGKSTVVP VPYEKMLRDQ SAVVVQGLPE GVAFKHPENY DLATLKWILE NKAGISFIIK RPFLEPKKHV GGRVMVTDAD RSILSPGGSC GPIKVKTEPT EDSGISLEMA AVTVKEESED PDYYQYNIQG SHHSSEGNEG TEMEVPAEG
Target Information
This gene encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. It is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11. 23. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7, 13 and 21.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BAP-135; Bruton tyrosine kinase-associated protein 135; BTK-associated protein, 135kD; General transcription factor II-I; GTFII-I; OTTHUMP00000209509; SPIN; SRF-Phox1-interacting protein; tfiii; Williams-Beuren syndrome chromosomal region 6 protein; Williams-Beuren syndrome chromosome region 6
Gene Aliases: BAP135; BTKAP1; DIWS; GTF2I; GTFII-I; IB291; SPIN; TFII-I; WBS; WBSCR6
UniProt ID: (Human) P78347
Entrez Gene ID: (Human) 2969
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
signal transduction
transition between slow and fast fiber
negative regulation of angiogenesis
negative regulation of cytosolic calcium ion concentration
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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