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Immunogen sequence: YASFDYEDAG YQTAELVKMD ILLNGNTVEE LVTVVHKDKA HSIGKAICER LKDSLPRQLF EIAIQAAIGS KIIARETVKA YRKNVLAKCY GGDITRKMKL LKRQAEGKKK LRKIGNVEVP KDA
Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one- codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: EF-4; Elongation factor 4 homolog; GTP-binding protein GUF1 homolog; GTPase GUF1; GTPase of unknown function 1; GUF1 GTPase homolog; Ribosomal back-translocase; Translation factor GUF1, mitochondrial
Gene Aliases: EF-4; GUF1
UniProt ID: (Human) Q8N442
Entrez Gene ID: (Human) 60558
Molecular Function:
translation initiation factor
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