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The GUSB gene encodes beta-glucuronidase (EC 3.2.1.31), a lysosomal hydrolase involved in the stepwise degradation of glucuronic acid-containing glycosaminoglycans. It is a tetrameric glycoprotein composed of identical subunits. The GUSB gene is mutated in mucopolysaccharidosis type VII (MPS7; MIM 253220).
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Protein Aliases: beta glucuronidase; beta-D-glucuronidase; Beta-G1; Beta-glucuronidase; glucuronidase, beta
Gene Aliases: BG; GUSB; MPS7
UniProt ID: (Human) P08236
Entrez Gene ID: (Human) 2990
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