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Product Details
13208-1-AP
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GZMM Fusion Protein Ag3982 (21-257 aa encoded by BC025701)
Conjugate
Form
Liquid
Concentration
0.44 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: SFGTQIIGG REVIPHSRPY MASLQRNGSH LCGGVLVHPK WVLTAAHCLA QRMAQLRLVL GLHTLDSPGL TFHIKAAIQH PRYKPVPALE NDLALLQLDG KVKPSRTIRP LALPSKRQVV AAGTRCSMAG WGLTHQGGRL SRVLRELDLQ VLDTRMCNNS RFWNGSLSPS MVCLAADSKD QAPCKGDSGG PLVCGKGRVL AGVLSFSSRV CTDIFKPPVA TAVAPYVSWI RKVTGRSA (21-257 aa encoded by BC025701 )
Target Information
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Granzyme M; granzyme M (lymphocyte met-ase 1); HU-Met-1; lymphoctye Met-ase 1; lymphocyte met-ase 1; Met-1 serine protease; Met-ase; Natural killer cell granular protease; RNK-Met-1
Gene Aliases: GZMM; LMET1; MET1; MMET-1
UniProt ID: (Human) P51124
Entrez Gene ID: (Human) 3004, (Mouse) 16904, (Rat) 29252
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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