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Product Details
H00003004-M03
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
4D11
Immunogen
GZMM (NP_005308, 85 a.a. approximately 193 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: DSPGLTFHIK AAIQHPRYKP VPALENDLAL LQLDGKVKPS RTIRPLALPS KRQVVAAGTR CSMAGWGLTH QGGRLSRVLR ELDLQVLDTR MCNNSRFWNG SLSPSMVCL
Target Information
Cleaves peptide substrates after methionine, leucine, and norleucine. Physiological substrates include EZR, alpha- tubulins and the apoptosis inhibitor BIRC5/Survivin. Promotes caspase activation and subsequent apoptosis of target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Granzyme M; granzyme M (lymphocyte met-ase 1); HU-Met-1; lymphocyte met-ase 1; Met-1 serine protease; Met-ase; Natural killer cell granular protease
Gene Aliases: GZMM; LMET1; MET1
UniProt ID: (Human) P51124
Entrez Gene ID: (Human) 3004
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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