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Invitrogen
Galectin 1 Recombinant Rabbit Monoclonal Antibody (JM13-37)
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 12
Galectin 1 Antibody (MA5-32779) in ICC/IF
Immunofluorescence analysis of Galectin 1 was performed using 70% confluent log phase MDA-MB-231 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Galectin 1 Recombinant Rabbit Monoclonal Antibody (JM13-37) (Product # MA5-32779) at 1:200 in 0.1% BSA... View More
Product Details
MA5-32779
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
JM13-37
Immunogen
Synthetic peptide within Human Galectin 1 aa 1-50
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2810056
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
Target Information
Galectin-1 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-1can be either monomeric or homodimeric and is found in a wide variety of cells and tissue types. Galectin-1 can control cell growth, proliferation, induce apoptosis of activated T cells while it can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 14 kDa laminin-binding protein; 14 kDa lectin; beta-galactoside binding protein; Beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; Gal-1; Galaptin; Galectin-1; Galectin1; H-Galectin-1; HBL; HLBP14; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin, galactose binding, soluble 1; lectin, galactoside binding soluble 1; lectin, galactoside-binding, soluble, 1; pm12; Putative MAPK-activating protein PM12; RL 14.5; S-Lac lectin 1
Gene Aliases: AA410090; Gal-1; GAL1; Galbp; galectin-1; GBP; L-14.5; L14; Lect14; LGALS1
UniProt ID: (Human) P09382, (Mouse) P16045, (Rat) P11762
Entrez Gene ID: (Human) 3956, (Mouse) 16852, (Rat) 56646
plasma cell differentiation
apoptotic process
signal transduction
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
T cell costimulation
multicellular organismal response to stress
positive regulation of erythrocyte aggregation
response to drug
regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
myoblast differentiation
positive regulation of viral entry into host cell
response to axon injury
cellular response to glucose stimulus
cellular response to organic cyclic compound
positive regulation of dendritic cell differentiation
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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