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Invitrogen
Ganglioside GM2 Chimeric Recombinant Rabbit Monoclonal Antibody (KM966)
FIGURE: 1 / 1
Ganglioside GM2 Chimeric Antibody (MA5-51582) in ICC/IF
Immunocytochemistry analysis of Ganglioside GM2 in paraformaldehyde fixed MCF7 cells using Ganglioside GM2 Chimeric Recombinant Rabbit Monoclocal Antibody (Product # MA5-51582) at a 1:1,000 dilution for 1h followed by Alexa Fluor 488 secondary antibody (1:1,500 dilution), showing nuclear staining. The nuclear stain is DAPI (blue). Panels show from left-right, top-bottom: primary antibody, DAPI, merged chann... View More
Product Details
MA5-51582
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG, kappa
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
KM966
Immunogen
This chimeric antibody was generated by cloning the variable heavy and light chain sequences of murine parent antibody KM696 (IgM) and expressing it as a mouse/human IgG1. The parent antibody was raised against human GM2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.02% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
Product Specific Information
Specificity: This antibody recognizes and binds ganglioside GM2.
Target Information
Ganglioside GM2 is a glycosphingolipid found in the plasma membrane of cells, particularly in the nervous system. It is composed of a ceramide lipid tail and a complex carbohydrate head group that contains sialic acid residues. The function of Ganglioside GM2 is not fully understood, but it is believed to play a role in cell signaling and communication, as well as in the formation and maintenance of the myelin sheath that surrounds nerve cells. Mutations in the genes responsible for the synthesis or degradation of Ganglioside GM2 can result in various neurological disorders, including Tay-Sachs disease and Sandhoff disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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