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Ghrelin Antibody (710266) in WB
Western blot analysis of Ghrelin in whole cell extracts from mouse stomach lysate using a Ghrelin Recombinant Rabbit Polyclonal Antibody (Product # 710266) at a dilution of 2 µg/mL. Samples were detected using chemiluminescence (ECL). Results show a band at ~13kDa.
Product Details
710266
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
Expi293
Class
Recombinant Superclonal
Type
Antibody
Clone
10HCLC
Immunogen
Peptide corresponding to amino acids 31-43 of human Ghrelin
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2532654
Product Specific Information
This antibody is predicted to react with mouse, rat, non-human primate and rabbit based on sequence homology.
Recombinant rabbit polyclonal antibodies are unique offerings from Thermo Fisher Scientific. They are comprised of a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds - the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies - all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody - recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets - a recombinant rabbit polyclonal antibody has a known mixture of light and heavy chains. The exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.
Target Information
GHRL encodes ghrelin-obestatin preproprotein, which generates ghrelin and obestatin. Ghrelin is an the ligand for the growth hormone secretagogue receptor type 1 and is involved in regulating growth hormone release. Ghrelin has an appeptite-stimulating effect and induces adiposity and stimulates gastric acid secretion. Obestatin may be the ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and can have an appetite-reducing effect resulting in decreased food intake.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AMCBX1; Appetite-regulating hormone; Fip3p; ghrelin 27; ghrelin 28; ghrelin, growth hormone secretagogue receptor ligand; ghrelin/obestatin; ghrelin/obestatin preprohormone; Growth hormone secretagogue; Growth hormone-releasing peptide; IKK-gamma; In2c-preproghrelin; IP1; IP2; IPD2; Motilin-related peptide; OTTHUMP00000207794; OTTHUMP00000207795; OTTHUMP00000207796; OTTHUMP00000207798; prepro-appetite regulatory hormone; preproghrelin; proghrelin; Protein M46
Gene Aliases: 2210006E23Rik; Ghr; GHRL; m46; MTLRP; MTLRPAP; UNQ524/PRO1066
UniProt ID: (Human) Q9UBU3, (Mouse) Q9EQX0
Entrez Gene ID: (Human) 51738, (Mouse) 58991
activation of MAPK activity
gastric acid secretion
negative regulation of endothelial cell proliferation
glucose metabolic process
G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
actin polymerization or depolymerization
adult feeding behavior
response to hormone
hormone-mediated signaling pathway
dendrite development
negative regulation of angiogenesis
growth hormone secretion
positive regulation of insulin secretion
regulation of response to food
positive regulation of appetite
negative regulation of interleukin-1 beta production
negative regulation of locomotion
positive regulation of multicellular organism growth
regulation of cell proliferation
negative regulation of circadian sleep/wake cycle, REM sleep
negative regulation of tumor necrosis factor biosynthetic process
negative regulation of apoptotic process
cortisol secretion
response to estrogen
negative regulation of interleukin-6 biosynthetic process
positive regulation of circadian sleep/wake cycle, non-REM sleep
negative regulation of insulin secretion
decidualization
negative regulation of inflammatory response
cartilage development
positive regulation of corticotropin secretion
positive regulation of cortisol secretion
positive regulation of synapse assembly
excitatory postsynaptic potential
positive regulation of growth hormone secretion
positive regulation of growth hormone receptor signaling pathway
positive regulation of protein tyrosine kinase activity
negative regulation of energy homeostasis
positive regulation of energy homeostasis
visual learning
positive regulation of response to food
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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