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Glutamate receptor 2 Polyclonal Antibody

Glutamate receptor 2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Glutamate receptor 2 Antibody (11994-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded mouse brain tissue slide using 11994-1-AP ( Glutamate receptor 2 antibody at dilution of 1:200 (under 40x lens). heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

Glutamate receptor 2 Antibody in Western Blot (WB)

Glutamate receptor 2 Antibody in Flow Cytometry (Flow)

Glutamate receptor 2 Antibody in Immunoprecipitation (IP)

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Product Details

11994-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 26 publications 26 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Flow Cytometry (Flow)

0.2 µg/1x10^6 cells

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Glutamate receptor 2 Fusion Protein Ag2662 (36-356 aa encoded by BC010574)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.42 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: GADQEYSAF RVGMVQFSTS EFRLTPHIDN LEVANSFAVT NAFCSQFSRG VYAIFGFYDK KSVNTITSFC GTLHVSFITP SFPTDGTHPF VIQMRPDLKG ALLSLVEYYQ WDKFAYLYDS DRGLSTLQAV LDSAAEKKWQ VTAINVGNIN NDKKDEMYRS LFQDLELKKE RRVILDCERD KVNDIVDQVI TIGKHVKGYH YIIANLGFTD GDLLKIQFGG ANVSGFQIVD YDDSLVSKFI ERWSTLEEKE YPGAHTTTIK YTSALTYDAV QVMTEAFRNL RKQRIEISRR GNAGDCLANP AVPWGQGVEI ERALKQVQVE GL (36-356 aa encoded by BC010574)

Target Information

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5 -methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain. The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

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Bioinformatics

Protein Aliases: AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; GluR-2; GluR-B; GluR-K2; glutamate receptor; Glutamate receptor 2; glutamate receptor B; glutamate receptor B flip isoform; Glutamate receptor ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 2; OTTHUMP00000165324; OTTHUMP00000220942; OTTHUMP00000220943

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Gene Aliases: GluA2; Glur-2; GluR-B; GluR-K2; GLUR2; GLURB; GRIA2; HBGR2

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UniProt ID: (Human) P42262, (Rat) P19491

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Entrez Gene ID: (Human) 2891, (Mouse) 14800, (Rat) 29627

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Function(s)

ionotropic glutamate receptor activity AMPA glutamate receptor activity excitatory extracellular ligand-gated ion channel activity extracellular-glutamate-gated ion channel activity protein binding receptor activity ion channel activity kainate selective glutamate receptor activity protein kinase binding PDZ domain binding identical protein binding calcium channel regulator activity transmembrane signal receptor

Process(es)

signal transduction chemical synaptic transmission ion transmembrane transport ionotropic glutamate receptor signaling pathway regulation of receptor recycling transport ion transport receptor internalization synaptic transmission, glutamatergic establishment of protein localization positive regulation of synaptic transmission protein tetramerization regulation of synaptic transmission, glutamatergic response to lithium ion response to fungicide

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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Glutamate receptor 2 Polyclonal Antibody

Glutamate receptor 2 Antibody (11994-1-AP) in IHC (P)

Product Details

11994-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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