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FIGURE: 1 / 1
Golgi protein 58k Antibody (PA5-97218) in WB
Western blot analysis of Golgi protein 58k in various lysates. Samples were incubated with Golgi protein 58k Polyclonal antibody (Product # PA5-97218) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Product Details
PA5-97218
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 412-541 of human FTCD (NP_0066481)
Conjugate
Form
Liquid
Concentration
2.83 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2809020
Product Specific Information
Immunogen sequence: DAEAFTAYLE AMRLPKNTPE EKDRRTAALQ EGLRRAVSVP LTLAETVASL WPALQELARC GNLACRSDLQ VAAKALEMGV FGAYFNVLIN LRDITDEAFK DQIHHRVSSL LQEAKTQAAL VLDCLETRQE; Positive Samples: LO2, Mouse liver, Mouse kidney, Rat liver, Rat kidney; Cellular Location: Cytoplasm, Golgi apparatus, centriole, centrosome, cytoskeleton, microtubule organizing center
Target Information
Golgi Protein, 58K is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 58 kDa microtubule-binding protein; Formimidoyltransferase-cyclodeaminase; formiminotransferase cyclodeaminase; Formiminotransferase-cyclodeaminase; FTCD; glutamate formiminotransferase; LCHC1
Gene Aliases: FTCD; LCHC1
UniProt ID: (Human) O95954, (Mouse) Q91XD4, (Rat) O88618
Entrez Gene ID: (Human) 10841, (Mouse) 14317, (Rat) 89833
histidine metabolic process
histidine catabolic process
cytoskeleton organization
metabolic process
cellular metabolic process
histidine catabolic process to glutamate and formamide
histidine catabolic process to glutamate and formate
tetrahydrofolate interconversion
folic acid-containing compound metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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