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FIGURE: 1 / 1
Granzyme A Antibody (MA5-24105) in ICC/IF
Immunocytochemistry analysis of Granzyme A in immersion fixed human peripheral blood mononuclear cells (PBMCs). Samples were incubated in Granzyme A monoclonal antibody (Product # MA5-24105) using a dilution of 8 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained (green).
Product Details
MA5-24105
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2B
Class
Monoclonal
Type
Antibody
Clone
356412
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Granzyme A Cys26-Val262
Conjugate
Form
Lyophilized
Concentration
0.5 mg/mL
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2609469
Product Specific Information
In direct ELISAs, no cross-reactivity with recombinant human Granzyme B, C, D, G, or H is observed.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTL tryptase; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; Fragmentin-1; granzyme 1; Granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; H factor; Hanukah factor serine protease); Hanukkah factor; HF
Gene Aliases: CTLA3; GZMA; HFSP
UniProt ID: (Human) P12544
Entrez Gene ID: (Human) 3001
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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