Product References
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Nature immunology
Scherer S,Oberle SG,Kanev K,Gerullis AK,Wu M,de Almeida GP,Puleston DJ,Baixauli F,Aly L,Greco A,Nizharadze T,Becker NB,Hoesslin MV,Donhauser LV,Berner J,Chu T,McNamara HA,Esencan Z,Roelli P,Wurmser C,Kleiter I,Vehreschild MJGT,Mayer CA,Knolle P,Klingenspor M,Fumagalli V,Iannacone M,Prlic M,Korn T,Pearce EL,Höfer T,Schulz AM,Zehn D
MHGB05 was used in Sample Preparation (FC/FACS) to show memory T cell precursors are resistant to pyrimidine starvation.
Wed Mar 01 00:00:00 EST 2023
Impact of mouse model tumor implantation site on acquired resistance to anti-PD-1 immune checkpoint therapy.
Frontiers in immunology
Denis M,Mathé D,Micoud M,Choffour PA,Grasselly C,Matera EL,Dumontet C
MHGB05 was used in flow cytometry to demonstrate several differences between SC and orthotopic models at basal state, which tend to become similar after therapy.
Tue Jan 31 00:00:00 EST 2023
Potential of Magnetic Hyperthermia to Stimulate Localized Immune Activation.
Small (Weinheim an der Bergstrasse, Germany)
Carter TJ,Agliardi G,Lin FY,Ellis M,Jones C,Robson M,Richard-Londt A,Southern P,Lythgoe M,Zaw Thin M,Ryzhov V,de Rosales RTM,Gruettner C,Abdollah MRA,Pedley RB,Pankhurst QA,Kalber TL,Brandner S,Quezada S,Mulholland P,Shevtsov M,Chester K
MHGB05 was used in Flow Cytometry to characterise immune cells from excised tumors and draining lymph nodes to evaluate the potential effects of MH on the immune landscape.
Thu Apr 01 00:00:00 EDT 2021
Control of SARS-CoV-2 infection after Spike DNA or Spike DNA+Protein co-immunization in rhesus macaques.
PLoS pathogens
Rosati M,Agarwal M,Hu X,Devasundaram S,Stellas D,Chowdhury B,Bear J,Burns R,Donohue D,Pessaint L,Andersen H,Lewis MG,Terpos E,Dimopoulos MA,Wlodawer A,Mullins JI,Venzon DJ,Pavlakis GN,Felber BK
MHGB05 was used in Flow Cytometry to test the immunogenicity and protective efficacy of DNA-based vaccine regimens expressing different prefusion-stabilized Wuhan-Hu-1 SARS-CoV-2 Spike antigens upon intramuscular injection followed by electroporation in rhesus macaques.
Wed Sep 01 00:00:00 EDT 2021
Flow cytometry-based ex vivo murine NK cell cytotoxicity assay.
STAR protocols
Wong P,Wagner JA,Berrien-Elliott MM,Schappe T,Fehniger TA
MHGB05 was used in Flow Cytometry to measure in vivo activated murine NK cells' ability to kill target cells ex vivo.
Fri Mar 19 00:00:00 EDT 2021
Effects of therapeutic vaccination on the control of SIV in rhesus macaques with variable responsiveness to antiretroviral drugs.
PloS one
Tunggal HC,Munson PV,O'Connor MA,Hajari N,Dross SE,Bratt D,Fuller JT,Bagley K,Fuller DH
MHGB05 was used in Flow Cytometry to indicate that mucosal immune responses, present prior to infection, can influence efficacy of antiretroviral therapy and the outcome of immunotherapeutic vaccination, suggesting that therapies capable of modulating host mucosal responses may be needed to achieve HIV cure.
Tue Nov 16 00:00:00 EST 2021
Senolytic CAR T cells reverse senescence-associated pathologies.
Nature
Amor C,Feucht J,Leibold J,Ho YJ,Zhu C,Alonso-Curbelo D,Mansilla-Soto J,Boyer JA,Li X,Giavridis T,Kulick A,Houlihan S,Peerschke E,Friedman SL,Ponomarev V,Piersigilli A,Sadelain M,Lowe SW
MHGB05 was used in Flow cytometry/Cell sorting to establish the therapeutic potential of senolytic CAR T cells for senescence-associated diseases.
Wed Jul 01 00:00:00 EDT 2020
Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy.
Immunity
Milner JJ,Toma C,He Z,Kurd NS,Nguyen QP,McDonald B,Quezada L,Widjaja CE,Witherden DA,Crowl JT,Shaw LA,Yeo GW,Chang JT,Omilusik KD,Goldrath AW
MHGB05 was used in Flow cytometry/Cell sorting to identify discrete lineages of intestinal antigen-specific CD8+ T cells, including a Blimp1hiId3lo tissue-resident effector cell population most prominent in the early phase of acute viral and bacterial infections and a molecularly distinct Blimp1loId3hi tissue-resident memory population that subsequently accumulated at later infection time points.
Tue May 19 00:00:00 EDT 2020
Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.
Cell reports
Felber BK,Lu Z,Hu X,Valentin A,Rosati M,Remmel CAL,Weiner JA,Carpenter MC,Faircloth K,Stanfield-Oakley S,Williams WB,Shen X,Tomaras GD,LaBranche CC,Montefiori D,Trinh HV,Rao M,Alam MS,Vandergrift NA,Saunders KO,Wang Y,Rountree W,Das J,Alter G,Reed SG,Aye PP,Schiro F,Pahar B,Dufour JP,Veazey RS,Marx PA,Venzon DJ,Shaw GM,Ferrari G,Ackerman ME,Haynes BF,Pavlakis GN
MHGB05 was used in Flow cytometry/Cell sorting to compare immunogenicity and protective efficacy of an HIV vaccine comprised of env and gag DNA and Env (Envelope) proteins by co-administration of the vaccine components in the same muscles or by separate administration of DNA + protein in contralateral sites.
Tue May 12 00:00:00 EDT 2020
Autoimmunity linked protein phosphatase PTPN22 as a target for cancer immunotherapy.
Journal for immunotherapy of cancer
Cubas R,Khan Z,Gong Q,Moskalenko M,Xiong H,Ou Q,Pai C,Rodriguez R,Cheung J,Chan AC
MHGB05 was used in Flow cytometry/Cell sorting to suggest that inhibition of PTPN22 phosphatase activity may provide an effective therapeutic option for cancer immunotherapy and that exploring genetic variants that shift immune tolerance thresholds may serve as a paradigm for finding new cancer immunotherapy targets.
Thu Oct 01 00:00:00 EDT 2020
Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity.
Cell reports
Wagner JA,Wong P,Schappe T,Berrien-Elliott MM,Cubitt C,Jaeger N,Lee M,Keppel CR,Marin ND,Foltz JA,Marsala L,Neal CC,Sullivan RP,Schneider SE,Keppel MP,Saucier N,Cooper MA,Fehniger TA
MHGB05 was used in Flow cytometry/Cell sorting to develop a tamoxifen-inducible, type-1-ILC-specific (Ncr1-targeted) cre mouse and combine this with Eomes-floxed mice.
Tue Jun 02 00:00:00 EDT 2020
Virus infection is controlled by hematopoietic and stromal cell sensing of murine cytomegalovirus through STING.
eLife
Piersma SJ,Poursine-Laurent J,Yang L,Barber GN,Parikh BA,Yokoyama WM
MHGB05 was used in Flow cytometry/Cell sorting to contrast anti-viral effects of MyD88 versus STING in distinct cell types that are infected with murine CMV (MCMV).
Wed Jul 29 00:00:00 EDT 2020
MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells.
Immunity
Berrien-Elliott MM,Sun Y,Neal C,Ireland A,Trissal MC,Sullivan RP,Wagner JA,Leong JW,Wong P,Mah-Som AY,Wong TN,Schappe T,Keppel CR,Cortez VS,Stamatiades EG,Li MO,Colonna M,Link DC,French AR,Cooper MA,Wang WL,Boldin MP,Reddy P,Fehniger TA
MHGB05 was used in Flow cytometry/Cell sorting to investigate whether the abundantly expressed microRNA-142 is a critical regulator of cytotoxic type 1 innate lymphoid cell biology.
Tue Sep 17 00:00:00 EDT 2019
Coexpression of Inhibitory Receptors Enriches for Activated and Functional CD8+ T Cells in Murine Syngeneic Tumor Models.
Cancer immunology research
Xiong H,Mittman S,Rodriguez R,Pacheco-Sanchez P,Moskalenko M,Yang Y,Elstrott J,Ritter AT,Müller S,Nickles D,Arenzana TL,Capietto AH,Delamarre L,Modrusan Z,Rutz S,Mellman I,Cubas R
MHGB05 was used in Flow cytometry/Cell sorting to show coexpression of inhibitory receptors can signify a population of heterogeneous cells that are exhausted and responsive to cancer treatment.
Sat Jun 01 00:00:00 EDT 2019
TCR and Inflammatory Signals Tune Human MAIT Cells to Exert Specific Tissue Repair and Effector Functions.
Cell reports
Leng T,Akther HD,Hackstein CP,Powell K,King T,Friedrich M,Christoforidou Z,McCuaig S,Neyazi M,Arancibia-Cárcamo CV,Hagel J,Powrie F,Peres RS,Millar V,Ebner D,Lamichhane R,Ussher J,Hinks TSC,Marchi E,Willberg C,Klenerman P
MHGB05 was used in Flow cytometry/Cell sorting to examine the impact of combinations of TCR-dependent and TCR-independent signals in human CD8+ MAIT cells.
Tue Sep 17 00:00:00 EDT 2019
Continuous activity of Foxo1 is required to prevent anergy and maintain the memory state of CD8+ T cells.
The Journal of experimental medicine
Delpoux A,Michelini RH,Verma S,Lai CY,Omilusik KD,Utzschneider DT,Redwood AJ,Goldrath AW,Benedict CA,Hedrick SM
MHGB05 was used in Flow cytometry/Cell sorting to show that FOXO1 is continuously required for all the phenotypic characteristics of memory-effector T cells.
Mon Feb 05 00:00:00 EST 2018
Chemotherapy Combines Effectively with Anti-PD-L1 Treatment and Can Augment Antitumor Responses.
Journal of immunology (Baltimore, Md. : 1950)
Cubas R,Moskalenko M,Cheung J,Yang M,McNamara E,Xiong H,Hoves S,Ries CH,Kim J,Gould S
MHGB05 was used in Flow cytometry/Cell sorting to evaluate the impact of chemotherapy alone or in combination with anti–PD-L1 in a responsive syngeneic tumor model.
Mon Oct 15 00:00:00 EDT 2018
Gag and env conserved element CE DNA vaccines elicit broad cytotoxic T cell responses targeting subdominant epitopes of HIV and SIV Able to recognize virus-infected cells in macaques.
Human vaccines & immunotherapeutics
Hu X,Lu Z,Valentin A,Rosati M,Broderick KE,Sardesai NY,Marx PA,Mullins JI,Pavlakis GN,Felber BK
MHGB05 was used in Flow cytometry/Cell sorting to study the cytotoxic T cell responses against conserved protein segments of SIV Gag and HIV Env following DNA vaccination.
Mon May 06 00:00:00 EDT 2019
Weak vaccinia virus-induced NK cell regulation of CD4 T cells is associated with reduced NK cell differentiation and cytolytic activity.
Virology
Hatfield SD,Daniels KA,O'Donnell CL,Waggoner SN,Welsh RM
MHGB05 was used in Flow cytometry/Cell sorting to suggest that natural killer (NK) cell regulation of adaptive immunity, while universal, may be limited with viruses that poorly activate NK cells.
Fri Jun 01 00:00:00 EDT 2018
FOXO1 opposition of CD8+ T cell effector programming confers early memory properties and phenotypic diversity.
Proceedings of the National Academy of Sciences of the United States of America
Delpoux A,Lai CY,Hedrick SM,Doedens AL
MHGB05 was used in Flow cytometry/Cell sorting to study the factors and steps controlling post infection CD8 T cell terminal effector versus memory differentiation.
Tue Oct 17 00:00:00 EDT 2017
Radiotherapy enhances natural killer cell cytotoxicity and localization in pre-clinical canine sarcomas and first-in-dog clinical trial.
Journal for immunotherapy of cancer
Canter RJ,Grossenbacher SK,Foltz JA,Sturgill IR,Park JS,Luna JI,Kent MS,Culp WTN,Chen M,Modiano JF,Monjazeb AM,Lee DA,Murphy WJ
MHGB05 was used in Flow cytometry/Cell sorting to assess radiotherapy (RT) plus local autologous natural killer (NK) transfer in canine sarcomas.
Tue Dec 19 00:00:00 EST 2017
Combined toll-like receptor 3/7/9 deficiency on host cells results in T-cell-dependent control of tumour growth.
Nature communications
Klein JC,Moses K,Zelinskyy G,Sody S,Buer J,Lang S,Helfrich I,Dittmer U,Kirschning CJ,Brandau S
MHGB05 was used in flow cytometry to find that TLR3, 7 and 9 deficiencies on host cells result in complete tumor regression and induction of anti-tumor immunity
Thu Mar 16 00:00:00 EDT 2017
Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.
Cancer immunology research
Doedens AL,Rubinstein MP,Gross ET,Best JA,Craig DH,Baker MK,Cole DJ,Bui JD,Goldrath AW
MHGB05 was used in Flow cytometry/Cell sorting to determine the molecular programming of IL15-resistant, tumor-infiltrating CD8+ T cells.
Fri Sep 02 00:00:00 EDT 2016
Preclinical Testing of Antihuman CD28 Fab' Antibody in a Novel Nonhuman Primate Small Animal Rodent Model of Xenogenic Graft-Versus-Host Disease.
Transplantation
Hippen KL,Watkins B,Tkachev V,Lemire AM,Lehnen C,Riddle MJ,Singh K,Panoskaltsis-Mortari A,Vanhove B,Tolar J,Kean LS,Blazar BR
MHGB05 was used in flow cytometry to discuss the assessment of species cross-reactive human agents in large animal graft-versus-host disease models
Thu Dec 01 00:00:00 EST 2016
Suppressor of cytokine signaling 4 (SOCS4) protects against severe cytokine storm and enhances viral clearance during influenza infection.
PLoS pathogens
Kedzierski L,Linossi EM,Kolesnik TB,Day EB,Bird NL,Kile BT,Belz GT,Metcalf D,Nicola NA,Kedzierska K,Nicholson SE
MHGB05 was used in Flow cytometry/Cell sorting to study the role of suppressor of cytokine signalling proteins in viral clearance during influenza infection.
Thu May 01 00:00:00 EDT 2014
NK cell killer Ig-like receptor repertoire acquisition and maturation are strongly modulated by HLA class I molecules.
Journal of immunology (Baltimore, Md. : 1950)
Sleiman M,Brons NH,Kaoma T,Dogu F,Villa-Forte A,Lenoble P,Hentges F,Kotsch K,Gadola SD,Vilches C,Zimmer J
MHGB05 was used in flow cytometry to quantify coexpression of different killer Ig-like molecules in patient natural killer cells with mutant TAP genes mediating deficient HLA class I expression
Sat Mar 15 00:00:00 EDT 2014
Regulatory T cells prevent Th2 immune responses and pulmonary eosinophilia during respiratory syncytial virus infection in mice.
Journal of virology
Durant LR,Makris S,Voorburg CM,Loebbermann J,Johansson C,Openshaw PJ
MHGB05 was used in flow cytometry to examine the functional effects of regulatory T cells during A2-strain respiratory syncytial virus infection.
Tue Oct 01 00:00:00 EDT 2013
The ARNT-STAT3 axis regulates the differentiation of intestinal intraepithelial TCRαβ⁺CD8αα⁺ cells.
Nature communications
Nakajima K,Maekawa Y,Kataoka K,Ishifune C,Nishida J,Arimochi H,Kitamura A,Yoshimoto T,Tomita S,Nagahiro S,Yasutomo K
MHGB05 was used in flow cytometry to assess the role of aryl hydrocarbon receptor nuclear translocator in intestinal intraepithelial T cells development.
Thu Jan 30 00:00:00 EST 2014
Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation.
Blood
Robb RJ,Lineburg KE,Kuns RD,Wilson YA,Raffelt NC,Olver SD,Varelias A,Alexander KA,Teal BE,Sparwasser T,Hammerling GJ,Markey KA,Koyama M,Clouston AD,Engwerda CR,Hill GR,MacDonald KP
MHGB05 was used in flow cytometry to identify a new population of CD8(+)FoxP3(+) T(reg).
Thu Jun 14 00:00:00 EDT 2012
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection.
Mucosal immunology
Loebbermann J,Thornton H,Durant L,Sparwasser T,Webster KE,Sprent J,Culley FJ,Johansson C,Openshaw PJ
MHGB05 was used in flow cytometry to report the effect of T regulatory cell depletion during acute respiratory syncytial virus infection
Thu Mar 01 00:00:00 EST 2012
Neutrophils sustain effective CD8(+) T-cell responses in the respiratory tract following influenza infection.
Immunology and cell biology
Tate MD,Brooks AG,Reading PC,Mintern JD
MHGB05 was used in flow cytometry to examine the impact of neutrophils on CD8 positive T-cell responses during influenza virus infection.
Wed Feb 01 00:00:00 EST 2012
IL-10+ CTLA-4+ Th2 inhibitory cells form in a Foxp3-independent, IL-2-dependent manner from Th2 effectors during chronic inflammation.
Journal of immunology (Baltimore, Md. : 1950)
Altin JA,Goodnow CC,Cook MC
MHGB05 was used in Flow cytometry/Cell sorting to investigate the mechanism and molecules involved in the formation of IL10+CTLA-4+Th2 inhibitory cells during chronic inflammation.
Fri Jun 01 00:00:00 EDT 2012
IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice.
PloS one
Loebbermann J,Schnoeller C,Thornton H,Durant L,Sweeney NP,Schuijs M,O'Garra A,Johansson C,Openshaw PJ
MHGB05 was used in flow cytometry to study the contribution of IL-10 in mice infected with respiratory syncytial virus
Mon Jul 23 00:00:00 EDT 2012
Type I-IFNs control GVHD and GVL responses after transplantation.
Blood
Robb RJ,Kreijveld E,Kuns RD,Wilson YA,Olver SD,Don AL,Raffelt NC,De Weerd NA,Lineburg KE,Varelias A,Markey KA,Koyama M,Clouston AD,Hertzog PJ,Macdonald KP,Hill GR
MHGB05 was used in flow cytometry to study the effects of type I-interferon on graft verses host disease.
Thu Sep 22 00:00:00 EDT 2011
A role for Blimp1 in the transcriptional network controlling natural killer cell maturation.
Blood
Kallies A,Carotta S,Huntington ND,Bernard NJ,Tarlinton DM,Smyth MJ,Nutt SL
MHGB05 was used in flow cytometry to examine the IRF4-Blimp1-Bcl6 regulatory axis in NK development
Thu Feb 10 00:00:00 EST 2011
Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome.
Blood
Antonelli LR,Mahnke Y,Hodge JN,Porter BO,Barber DL,DerSimonian R,Greenwald JH,Roby G,Mican J,Sher A,Roederer M,Sereti I
MHGB05 was used in flow cytometry to identify immunologic correlates of immune reconstitution inflammatory syndrome in HIV patients
Thu Nov 11 00:00:00 EST 2010
Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway.
The Journal of experimental medicine
Hubert S,Rissiek B,Klages K,Huehn J,Sparwasser T,Haag F,Koch-Nolte F,Boyer O,Seman M,Adriouch S
MHGB05 was used in flow cytometry to report that NAD(+) regulates the survival, phenotype, and function of T regulatory cells via the ART2-P2X7 pathway
Mon Nov 22 00:00:00 EST 2010
Selective depletion of Foxp3+ regulatory T cells improves effective therapeutic vaccination against established melanoma.
Cancer research
Klages K,Mayer CT,Lahl K,Loddenkemper C,Teng MW,Ngiow SF,Smyth MJ,Hamann A,Huehn J,Sparwasser T
MHGB05 was used in flow cytometry to test if selective depletion of Foxp3(+) Tregs reduces cancer
Fri Oct 15 00:00:00 EDT 2010
Analysis of A47, an immunoprevalent protein of vaccinia virus, leads to a reevaluation of the total antiviral CD8+ T cell response.
Journal of virology
Yuen TJ,Flesch IE,Hollett NA,Dobson BM,Russell TA,Fahrer AM,Tscharke DC
MHGB05 was used in flow cytometry to investigate the function of the Vaccinia virus A47L gene
Fri Oct 01 00:00:00 EDT 2010
Emergence of simian immunodeficiency virus-specific cytotoxic CD4+ T cells and increased humoral responses correlate with control of rebounding viremia in CD8-depleted macaques infected with Rev-independent live-attenuated simian immunodeficiency virus.
Journal of immunology (Baltimore, Md. : 1950)
von Gegerfelt A,Valentin A,Alicea C,Van Rompay KK,Marthas ML,Montefiori DC,Pavlakis GN,Felber BK
MHGB05 was used in flow cytometry to investigate immune mechanisms responsible for viral control in Indian rhesus macaques infected SIV
Wed Sep 15 00:00:00 EDT 2010
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Tait ED,Jordan KA,Dupont CD,Harris TH,Gregg B,Wilson EH,Pepper M,Dzierszinski F,Roos DS,Hunter CA
MHGB05 was used in flow cytometry to investigate the different immune responses when mice are infected with type I or type II strains of T. gondii
Sun Aug 01 00:00:00 EDT 2010
Impact of age, gender, and race on circulating γδ T cells.
Human immunology
Cairo C,Armstrong CL,Cummings JS,Deetz CO,Tan M,Lu C,Davis CE,Pauza CD
MHGB05 was used in flow cytometry to study Vgamma2Vdelta2 T cells from Caucasian or African American donors
Fri Oct 01 00:00:00 EDT 2010
Heterogeneity in phenotype and function of CD8+ and CD4/CD8 double-negative Natural Killer T cell subsets in sooty mangabeys.
Journal of medical primatology
Rout N,Else JG,Yue S,Connole M,Exley MA,Kaur A
MHGB05 was used in flow cytometry to characterize natural killer T subsets in sooty mangabey
Sun Aug 01 00:00:00 EDT 2010
The regulatory T-cell response during acute retroviral infection is locally defined and controls the magnitude and duration of the virus-specific cytotoxic T-cell response.
Blood
Zelinskyy G,Dietze KK,Hüsecken YP,Schimmer S,Nair S,Werner T,Gibbert K,Kershaw O,Gruber AD,Sparwasser T,Dittmer U
MHGB05 was used in flow cytometry to study the influence of Treg on pathogen-specific CD8+ T-cell responses in vivo
Thu Oct 08 00:00:00 EDT 2009
Granzyme A expression reveals distinct cytolytic CTL subsets following influenza A virus infection.
European journal of immunology
Moffat JM,Gebhardt T,Doherty PC,Turner SJ,Mintern JD
MHGB05 was used in flow cytometry to examine granzyme expression during influenza infection
Fri May 01 00:00:00 EDT 2009
Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21.
Journal of immunology (Baltimore, Md. : 1950)
Hagn M,Schwesinger E,Ebel V,Sontheimer K,Maier J,Beyer T,Syrovets T,Laumonnier Y,Fabricius D,Simmet T,Jahrsdörfer B
MHGB05 was used in flow cytometry to identify conditions in which granzyme B is produced by human B cells
Sat Aug 01 00:00:00 EDT 2009
Single-dose protection against Plasmodium berghei by a simian adenovirus vector using a human cytomegalovirus promoter containing intron A.
Journal of virology
Sridhar S,Reyes-Sandoval A,Draper SJ,Moore AC,Gilbert SC,Gao GP,Wilson JM,Hill AV
MHGB05 was used in flow cytometry to analyze protection against Plasmodium berghei by a single-dose simian adenovirus vector using a human cytomegalovirus promoter containing intron A
Tue Apr 01 00:00:00 EDT 2008
Functional regulatory T cells accumulate in aged hosts and promote chronic infectious disease reactivation.
Journal of immunology (Baltimore, Md. : 1950)
Lages CS,Suffia I,Velilla PA,Huang B,Warshaw G,Hildeman DA,Belkaid Y,Chougnet C
MHGB05 was used in flow cytometry to characterize Tregs from older subjects and mice.
Fri Aug 01 00:00:00 EDT 2008
Cell cycle-related acquisition of cytotoxic mediators defines the progressive differentiation to effector status for virus-specific CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950)
Jenkins MR,Mintern J,La Gruta NL,Kedzierska K,Doherty PC,Turner SJ
MHGB05 was used in flow cytometry to measure effector gene expression early after CTL activation
Mon Sep 15 00:00:00 EDT 2008
The level of friend retrovirus replication determines the cytolytic pathway of CD8+ T-cell-mediated pathogen control.
Journal of virology
Zelinskyy G,Balkow S,Schimmer S,Werner T,Simon MM,Dittmer U
MHGB05 was used in flow cytometry to assess the contributions of viral replication levels in the induction and activation of cytotoxic T cells
Thu Nov 01 00:00:00 EDT 2007
Heterogeneity of effector phenotype for acute phase and memory influenza A virus-specific CTL.
Journal of immunology (Baltimore, Md. : 1950)
Jenkins MR,Kedzierska K,Doherty PC,Turner SJ
MHGB05 was used in flow cytometry to explore how naive, effector, and memory T cells differ in cytotoxic potential
Sun Jul 01 00:00:00 EDT 2007
Attenuation of CD8(+) T-cell function by CD4(+)CD25(+) regulatory T cells in B-cell non-Hodgkin's lymphoma.
Cancer research
Yang ZZ,Novak AJ,Ziesmer SC,Witzig TE,Ansell SM
MHGB05 was used in flow cytometry to study CD4(+) CD25 (+) regulatory T cells in B-cell non-Hodgkin's lymphoma and attenuation of CD8(+) T-cell function
Sun Oct 15 00:00:00 EDT 2006
Development of hemophagocytic lymphohistiocytosis in triplets infected with HHV-8.
Blood
Grossman WJ,Radhi M,Schauer D,Gerday E,Grose C,Goldman FD
MHGB05 was used in flow cytometry to analyze triplets infected with HHV-8 and the development of hemophagocytic lymphohistiocytosis
Mon Aug 15 00:00:00 EDT 2005
Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood.
European journal of immunology
Bratke K,Kuepper M,Bade B,Virchow JC,Luttmann W
MHGB05 was used in flow cytometry to use flow cytometry to study granzyme A, B, and K expression in human peripheral blood lymphocytes
Thu Sep 01 00:00:00 EDT 2005
CD8+ T-cell dysfunction due to cytolytic granule deficiency in persistent Friend retrovirus infection.
Journal of virology
Zelinskyy G,Robertson SJ,Schimmer S,Messer RJ,Hasenkrug KJ,Dittmer U
MHGB05 was used in flow cytometry to examine impairment of cytotoxic CD8+ T-cell effector function during chronic Friend virus infection
Mon Aug 01 00:00:00 EDT 2005
Cutting edge: contact-mediated suppression by CD4+CD25+ regulatory cells involves a granzyme B-dependent, perforin-independent mechanism.
Journal of immunology (Baltimore, Md. : 1950)
Gondek DC,Lu LF,Quezada SA,Sakaguchi S,Noelle RJ
MHGB05 was used in flow cytometry to investigate the role of granzyme B in T regulatory cell-mediated suppression
Tue Feb 15 00:00:00 EST 2005
Development and migration of protective CD8+ T cells into the nervous system following ocular herpes simplex virus-1 infection.
Journal of immunology (Baltimore, Md. : 1950)
Lang A,Nikolich-Zugich J
MHGB05 was used in flow cytometry to analyze ocular herpes simplex virus-1 infection and the migration and development of protective CD8+ T cells into the nervous system
Tue Mar 01 00:00:00 EST 2005
Tracking antigen-specific CD8 T lymphocytes in the lungs of mice vaccinated with the Mtb72F polyprotein.
Infection and immunity
Irwin SM,Izzo AA,Dow SW,Skeiky YA,Reed SG,Alderson MR,Orme IM
MHGB05 was used in flow cytometry to evaluate the tuberculosis vaccine candidate Mtb72F
Thu Sep 01 00:00:00 EDT 2005
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells.
Blood
Grossman WJ,Verbsky JW,Tollefsen BL,Kemper C,Atkinson JP,Ley TJ
MHGB05 was used in flow cytometry to study granzymes A and B and differential expression in human cytotoxic lymphocyte subsets and T regulatory cells
Mon Nov 01 00:00:00 EST 2004
