Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
Granzyme H Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 2
Granzyme H Antibody (PA5-83074) in WB
Molecular oncology 2022 -
3 Fig. Protein profiling of extracellular vesicles in relation to progression-free survival. Extracellular vesicles (EVs) isolated from plasma samples from metastatic urothelial cancer (mUC) patients at day 21 were subjected to proximity extension assay (PEA) protein profiling with the Oncology II (r) assay (see Section 2.4). (A) Rank regression analyses of protein signatures in EVs related to progression-f... View More
Product Details
PA5-83074
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human GZMH. Recombinant protein control fragment (Product #RP-88868).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Anitgen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2790230
Product Specific Information
Immunogen sequence: HPAYNPKNFS NDIMLLQLER KAKWTTAVRP LRLPSSKAQV KPGQLCSVAG WGYVSMSTLA TTLQEVLLTV QKDCQCERLF HGNYSRATEI CVGDPKKTQT GFKGDSGGPL VCKDVAQGIL SYGNKKGTPP GVYIKVSHFL PWIKRTM
Target Information
This gene encodes a member of the peptidase S1 family of serine proteases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate a chymotrypsin-like protease. This protein is reported to be constitutively expressed in the NK (natural killer) cells of the immune system and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. This gene is present in a gene cluster with another member of the granzyme subfamily on chromosome 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cathepsin G-like 2; cathepsin G-like 2, protein h-CCPX; CCP-X; CSP-C; CTSGL2; Cytotoxic serine protease C; Cytotoxic T-lymphocyte proteinase; cytotoxic T-lymphocyte-associated serine esterase 1; cytotoxin serine protease-C; Granzyme H; granzyme H (cathepsin G-like 2, protein h-CCPX)
Gene Aliases: CCP-X; CGL-2; CGL2; CSP-C; CTLA1; CTSGL2; GZMH
UniProt ID: (Human) P20718
Entrez Gene ID: (Human) 2999
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support