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Product Details
H00003043-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG3, kappa
Class
Monoclonal
Type
Antibody
Clone
2H3
Immunogen
HBB (AAH07075, 38 a.a. approximately 147 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: WTQRFFESFG DLSTPDAVMG NPKVKAHGKK VLGAFSDGLA HLDNLKGTFA TLSELHCDKL HVDPENFRLL GNVLVCVLAH HFGKEFTPPV QAAYQKVVAG VANALPHKYH
Target Information
The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon-gamma-G-gamma-A-delta-beta-3'.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: beta globin chain; Beta-globin; hemoglobin beta; Hemoglobin beta chain; Hemoglobin subunit beta; hemoglobin, beta
Gene Aliases: beta-globin; CD113t-C; HBB
UniProt ID: (Human) P68871
Entrez Gene ID: (Human) 3043
receptor-mediated endocytosis
blood coagulation
regulation of blood pressure
positive regulation of cell death
oxygen transport
bicarbonate transport
nitric oxide transport
response to hydrogen peroxide
hydrogen peroxide catabolic process
positive regulation of nitric oxide biosynthetic process
regulation of blood vessel size
protein heterooligomerization
renal absorption
platelet aggregation
cellular oxidant detoxification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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