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Search Thermo Fisher Scientific
A suggested positive control is mouse brain tissue lysate.
PA5-34480 can be used with blocking peptide PEP-1522.
HEPACAM2 (Hepatocyte cell adhesion molecule 2), a type I N-linked transmembrane glycoprotein, belongs to the immunoglobulin superfamily. The exact function of HEPACAM2 is currently unknown, but the related protein HEPACAM forms cishomodimers on the cell surface to regulate the cell adhesion and may inhibit cell growth through suppression of cell proliferation. HEPACAM and HEPACAM2 mRNA are differentially regulated in canine tumors, with HEPACAM2 mRNA showing increased levels in adenomas, but decreased levels in metastatic carcinomas compared to normal tissues, while HEPACAM protein levels decreased in adenomas. It is therefore likely that HEPACAM2 plays a different role than HEPACAM in the development and progression to tumors.
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Protein Aliases: HEPACAM family member 2; Mitotic kinetics regulator
Gene Aliases: AI987662; HEPACAM2; MIKI; RGD1305697; UNQ305/PRO346
UniProt ID: (Human) A8MVW5, (Mouse) Q4VAH7
Entrez Gene ID: (Human) 253012, (Rat) 296846, (Mouse) 101202
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