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Product Details
PA5-72635
Product Specifications
Species Reactivity
Zebrafish
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide between 295-322 amino acids from the C-terminal region of DANRE hey2
Conjugate
Form
Liquid
Concentration
0.34 mg/mL
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718489
Target Information
Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: basic helix-loop-helix transcription factor; gridlock; h hHRT2; hairy/enhancer-of-split related with YRPW motif 2; Hairy/enhancer-of-split related with YRPW motif protein 2; Herp2; Protein gridlock
Gene Aliases: grl; hey2; zgc:136746
UniProt ID: (Zebrafish) Q9I9L0
Entrez Gene ID: (Zebrafish) 58146
blood vessel development
vasculogenesis
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
Notch signaling pathway
multicellular organism development
heart development
anterior/posterior pattern specification
dorsal aorta morphogenesis
negative regulation of transcription, DNA-templated
blood vessel morphogenesis
artery morphogenesis
regulation of neurogenesis
artery development
Notch signaling pathway involved in arterial endothelial cell fate commitment
circulatory system development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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