HIF1a Monoclonal Antibody (1H3C12)

transcription factor activity, transcription factor binding transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding enzyme binding protein kinase binding ubiquitin protein ligase binding protein complex binding histone acetyltransferase binding nuclear hormone receptor binding histone deacetylase binding sequence-specific DNA binding protein heterodimerization activity Hsp90 protein binding basic helix-loop-helix transcription factor

negative regulation of transcription from RNA polymerase II promoter angiogenesis response to hypoxia neural crest cell migration epithelial to mesenchymal transition embryonic placenta development B-1 B cell homeostasis positive regulation of endothelial cell proliferation heart looping positive regulation of neuroblast proliferation connective tissue replacement involved in inflammatory response wound healing outflow tract morphogenesis cardiac ventricle morphogenesis lactate metabolic process regulation of transcription, DNA-templated transcription from RNA polymerase II promoter cellular iron ion homeostasis acute-phase response signal transduction lactation visual learning response to salt stress response to X-ray regulation of gene expression vascular endothelial growth factor production positive regulation of vascular endothelial growth factor production positive regulation of gene expression positive regulation of epithelial cell migration positive regulation of receptor biosynthetic process response to auditory stimulus response to purine-containing compound response to muscle activity positive regulation of macroautophagy axonal transport of mitochondrion neural fold elevation formation cerebral cortex development negative regulation of bone mineralization positive regulation of vascular endothelial growth factor receptor signaling pathway negative regulation of TOR signaling response to estradiol oxygen homeostasis positive regulation of chemokine production cellular response to insulin stimulus regulation of transforming growth factor beta2 production collagen metabolic process embryonic hemopoiesis cellular response to drug positive regulation of insulin secretion involved in cellular response to glucose stimulus hemoglobin biosynthetic process mRNA transcription from RNA polymerase II promoter positive regulation of apoptotic process response to alkaloid regulation of transcription from RNA polymerase II promoter in response to oxidative stress response to estrogen positive regulation of erythrocyte differentiation positive regulation of angiogenesis positive regulation of cell size positive regulation of glycolytic process positive regulation of transcription, DNA-templated negative regulation of vasoconstriction negative regulation of growth positive regulation of transcription from RNA polymerase II promoter muscle cell cellular homeostasis positive regulation of hormone biosynthetic process digestive tract morphogenesis positive regulation of smooth muscle cell proliferation positive regulation of nitric-oxide synthase activity cartilage development response to glucocorticoid elastin metabolic process maternal process involved in female pregnancy intestinal epithelial cell maturation response to fungicide epithelial cell differentiation involved in mammary gland alveolus development iris morphogenesis retina vasculature development in camera-type eye regulation of transcription from RNA polymerase II promoter in response to hypoxia positive regulation of transcription from RNA polymerase II promoter in response to hypoxia positive regulation of chemokine-mediated signaling pathway negative regulation of thymocyte apoptotic process cellular response to hydrogen peroxide cellular response to lipopolysaccharide cellular response to carbon monoxide cellular response to nitrite cellular response to electrical stimulus cellular response to mechanical stimulus cellular response to cobalt ion cellular response to glucose stimulus cellular response to interleukin-1 cellular response to organic cyclic compound cellular response to hypoxia cellular response to light stimulus dopaminergic neuron differentiation response to anesthetic cellular response to toxic substance hypoxia-inducible factor-1alpha signaling pathway regulation of cellular response to hypoxia positive regulation of pri-miRNA transcription from RNA polymerase II promoter negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway positive regulation of mitophagy regulation of aerobic respiration cellular response to cyanide negative regulation of reactive oxygen species metabolic process negative regulation of mesenchymal cell apoptotic process