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Invitrogen
HIV1 gp120 Polyclonal Antibody
Product Details
PA1-7218
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Published species
Not Applicable
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Purified native gp120 from strain IIIB.
Conjugate
Form
Liquid
Concentration
5.0 mg/mL
Purification
IgG fraction
Storage buffer
PBS, pH 7.2
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_559501
Product Specific Information
PA1-7218 detects the HIV1 gp120. This antibody does not cross-react with human T or B cells.
PA1-7218 has been successfully used in Western blot and ELISA procedures.
The PA1-7218 immunogen is purified native gp120 from strain IIIB.
Recommended storage of up to 6 months at 2-8ºC. For long term storage, aliquot and freeze. avoiding freeze/thaw cycles.
Target Information
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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