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Product Details
MA5-17015
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Rat
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
4B5
Immunogen
TrpE-Fusion protein produced in X63Ag8.653 cells
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2538487
Product Specific Information
MA5-17015 recognizes HIV-2 Nef and does not cross react with HIV-1 Nef.
MA5-17015 has been successfully used in immunoprecipitation and Western blot applications.
The MA5-17015 immunogen is a TrpE-Fusion protein produced in X63Ag8.653 cells.
Target Information
Nef is a multifunctional protein of 27 kDa in HIV-1 and 35 kDa in HIV-2. It induces the endocytosis of CD4 Receptor and reduces the MHC-1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HIV-2; HIV-2 nef; HIV2 nef protein; Nefprotein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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