Proteintech

HMOX2 Polyclonal Antibody

HMOX2 Antibody in Immunocytochemistry (ICC/IF)

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HMOX2 Antibody (14817-1-AP) in ICC/IF

Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 14817-1-AP (HMOX2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L).

HMOX2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

HMOX2 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

14817-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

View 6 publications 6 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:500

Immunocytochemistry (ICC/IF)

1:50-1:500

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

HMOX2 Fusion Protein Ag6575 (1-293 aa encoded by BC002396)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.34 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MSAEVETSE GVDESEKKNS GALEKENQMR MADLSELLKE GTKEAHDRAE NTQFVKDFLK GNIKKELFKL ATTALYFTYS ALEEEMERNK DHPAFAPLYF PMELHRKEAL TKDMEYFFGE NWEEQVQCPK AAQKYVERIH YIGQNEPELL VAHAYTRYMG DLSGGQVLKK VAQRALKLPS TGEGTQFYLF ENVDNAQQFK QLYRARMNAL DLNMKTKERI VEEANKAFEY NMQIFNELDQ AGSTLARETL EDGFPVHDGK GDMRKCPFYA AEQDKGALEG SSCPFRTAMA VLRK (1-293 aa encoded by BC002396)

Target Information

Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Several alternatively spliced transcript variants encoding three different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Metabolic-scale gene activation screens identify SLCO2B1 as a heme transporter that enhances cellular iron availability.

Molecular cell

Unlu G,Prizer B,Erdal R,Yeh HW,Bayraktar EC,Birsoy K

Thu Aug 04 00:00:00 EDT 2022

Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage.

Acta pharmaceutica Sinica. B

Bakalarz D,Surmiak M,Yang X,Wójcik D,Korbut E,Śliwowski Z,Ginter G,Buszewicz G,Brzozowski T,Cieszkowski J,Głowacka U,Magierowska K,Pan Z,Wang B,Magierowski M

Mon Feb 01 00:00:00 EST 2021

Evidence for Cytoprotective Effect of Carbon Monoxide Donor in the Development of Acute Esophagitis Leading to Acute Esophageal Epithelium Lesions.

Cells

Magierowska K,Bakalarz D,Wójcik D,Korbut E,Danielak A,Głowacka U,Pajdo R,Buszewicz G,Ginter G,Surmiak M,Kwiecień S,Chmura A,Magierowski M,Brzozowski T

Tue May 12 00:00:00 EDT 2020

Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.

Oxidative medicine and cellular longevity

Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J

Tue Sep 18 00:00:00 EDT 2018

Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.

Oxidative medicine and cellular longevity

Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J

Tue Sep 18 00:00:00 EDT 2018

Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.

Oxidative medicine and cellular longevity

Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J

Tue Sep 18 00:00:00 EDT 2018

Hydrogen Sulfide Abrogates Hemoglobin-Lipid Interaction in Atherosclerotic Lesion.

Oxidative medicine and cellular longevity

Potor L,Nagy P,Méhes G,Hendrik Z,Jeney V,Pethő D,Vasas A,Pálinkás Z,Balogh E,Gyetvai Á,Whiteman M,Torregrossa R,Wood ME,Olvasztó S,Nagy P,Balla G,Balla J

Tue Sep 18 00:00:00 EDT 2018

Role of epithelial Na+ channels in endothelial function.

Journal of cell science

Guo D,Liang S,Wang S,Tang C,Yao B,Wan W,Zhang H,Jiang H,Ahmed A,Zhang Z,Gu Y

Fri Jan 15 00:00:00 EST 2016

Role of epithelial Na+ channels in endothelial function.

Journal of cell science

Guo D,Liang S,Wang S,Tang C,Yao B,Wan W,Zhang H,Jiang H,Ahmed A,Zhang Z,Gu Y

Fri Jan 15 00:00:00 EST 2016

Carbon Monoxide (CO) Released from Tricarbonyldichlororuthenium (II) Dimer (CORM-2) in Gastroprotection against Experimental Ethanol-Induced Gastric Damage.

PloS one

Magierowska K,Magierowski M,Hubalewska-Mazgaj M,Adamski J,Surmiak M,Sliwowski Z,Kwiecien S,Brzozowski T

Mon Jun 06 00:00:00 EDT 2016

Carbon Monoxide (CO) Released from Tricarbonyldichlororuthenium (II) Dimer (CORM-2) in Gastroprotection against Experimental Ethanol-Induced Gastric Damage.

PloS one

Magierowska K,Magierowski M,Hubalewska-Mazgaj M,Adamski J,Surmiak M,Sliwowski Z,Kwiecien S,Brzozowski T

Mon Jun 06 00:00:00 EDT 2016

Bioinformatics

Protein Aliases: heme oxygenase (decycling) 2; Heme oxygenase 2; heme oxygenase-2 non-reducing isoform; HMOX 2; HO 2; HO-2

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Gene Aliases: HMOX2; HO-2; HO2

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UniProt ID: (Human) P30519, (Rat) P23711, (Mouse) O70252

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Entrez Gene ID: (Human) 3163, (Rat) 79239, (Mouse) 15369

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Function(s)

heme oxygenase (decyclizing) activity protein binding metal ion binding oxidoreductase activity oxygenase

Process(es)

response to hypoxia heme oxidation cellular iron ion homeostasis heme catabolic process response to oxidative stress oxidation-reduction process

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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HMOX2 Polyclonal Antibody

HMOX2 Antibody (14817-1-AP) in ICC/IF

Product Details

14817-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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