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HOMER1 Antibody (CF811745) in IHC (P)
Immunohistochemical staining of paraffin-embedded human embryonic cerebellum within the normal limits using anti-HOMER1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA811745)(1:500)
Product Details
CF811745
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
OTI7G10
Immunogen
Human recombinant protein fragment corresponding to amino acids 1-354 of human HOMER1 produced in E.coli.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
HOMER1 is a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: homer homolog 1; Homer protein homolog 1; homer, neuronal immediate early gene, 1; Homer-1; immediate early gene protein Homer1A; PSD-Zip45; scaffold protein; VASP/Ena-related gene up-regulated during seizure and LTP 1; Vesl-1
Gene Aliases: HOMER; homer-1; HOMER1; HOMER1A; HOMER1B; HOMER1C; HOMER1F; PSD-Zip45; SYN47; Ves-1; Vesl; Vesl-1; Vesl1
UniProt ID: (Human) Q86YM7, (Mouse) Q9Z2Y3, (Rat) Q9Z214
Entrez Gene ID: (Human) 9456, (Mouse) 26556, (Rat) 29546
skeletal muscle contraction
G-protein coupled glutamate receptor signaling pathway
protein localization to synapse
behavioral response to cocaine
skeletal muscle fiber development
chemical homeostasis within a tissue
response to calcium ion
positive regulation of calcium ion transport
regulation of calcium ion import
regulation of store-operated calcium entry
regulation of cation channel activity
phospholipase C-activating G-protein coupled glutamate receptor signaling pathway
chemical synaptic transmission
positive regulation of signal transduction
circadian rhythm
response to nicotine
response to cocaine
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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