Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
16673-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HPSE Fusion Protein Ag10167 (159-543 aa encoded by BC051321)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KFKNSTYSR SSVDVLYTFA NCSGLDLIFG LNALLRTADL QWNSSNAQLL LDYCSSKGYN ISWELGNEPN SFLKKADIFI NGSQLGEDFI QLHKLLRKST FKNAKLYGPD VGQPRRKTAK MLKSFLKAGG EVIDSVTWHH YYLNGRTATR EDFLNPDVLD IFISSVQKVF QVVESTRPGK KVWLGETSSA YGGGAPLLSD TFAAGFMWLD KLGLSARMGI EVVMRQVFFG AGNYHLVDEN FDPLPDYWLS LLFKKLVGTK VLMASVQGSK RRKLRVYLHC TNTDNPRYKE GDLTLYAINL HNVTKYLRLP YPFSNKQVDK YLLRPLGPHG LLSKSVQLNG LTLKMVDDQT LPPLMEKPLR PGSSLGLPAF SYSFFVIRNA KVAACI (159-543 aa encoded by BC051321)
Target Information
Stem cells offer a therapeutic promise for many diseases. In the case of diabetes, stem cells offer the promise that beta cells may be generated ex vivo for the possible transplantation and cure of Type I diabetes (Couri CE, et al. ). For this to happen, stem cells will need to be isolated and expanded, they will need to be differentiated toward the beta cell lineage, and the differentiated cell progeny used for transplantation may need to be isolated from complex cell mixtures following differentiation. Appropriate markers targeting cell surface molecules on developing and mature pancreatic cells will be required for such research.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Endo-glucoronidase; endoglycosidase heparanase; Heparanase; Heparanase-1; heparanase-like; Hpa1
Gene Aliases: HEP; HPA; HPA1; HPR1; HPSE; HPSE1; HSE1
UniProt ID: (Human) Q9Y251, (Mouse) Q6YGZ1, (Rat) Q71RP1
Entrez Gene ID: (Human) 10855, (Mouse) 15442, (Rat) 64537
carbohydrate metabolic process
glycosaminoglycan catabolic process
proteoglycan metabolic process
cell-matrix adhesion
positive regulation of vascular endothelial growth factor production
positive regulation of blood coagulation
extracellular matrix organization
heparan sulfate proteoglycan catabolic process
positive regulation of osteoblast proliferation
regulation of hair follicle development
positive regulation of hair follicle development
positive regulation of protein kinase B signaling
angiogenesis involved in wound healing
vascular wound healing
cell adhesion
wound healing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support