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Product Details
BS-6664R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human HRH2, amino acids 161-259.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
H2 Histamine Receptor stimulates adenylate cyclase activity and leads to the release of acids in the stomach. It is also involved in GI motility and intestinal secretion. Treatments for acid-peptic disorders are based on the inhibition of histamine H2 receptor activity. The 3-untranslated region may be involved in differential expression. Histamine H2 receptor has been reported to be expressed in bone marrow, brain, heart, lymph node, nose, placenta, spinal cord, and stomach. An EST has been isolated from a kidney library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: gastric receptor 1; Gastric receptor I; H2R; HH2R; Histamine H2 receptor; histamine receptor
Gene Aliases: H2R; HRH2
UniProt ID: (Human) P25021, (Mouse) P97292
Entrez Gene ID: (Human) 3274, (Rat) 25461, (Mouse) 15466
histamine-induced gastric acid secretion
gastrin-induced gastric acid secretion
epithelial cell morphogenesis
immune response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
memory
visual learning
positive regulation of vasoconstriction
regulation of synaptic plasticity
digestive tract development
gland development
toxin transport
gastric acid secretion
G-protein coupled receptor signaling pathway
cellular response to histamine
negative regulation of arachidonic acid secretion
synaptic transmission, dopaminergic
signal transduction
adenylate cyclase-activating dopamine receptor signaling pathway
sensory perception of chemical stimulus
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
phospholipase C-activating dopamine receptor signaling pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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