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Product Details
PA5-33844
Product Specifications
Species Reactivity
Human,
Non-human primate
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human HRH2 / Histamine H2 Receptor.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551213
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%) Mouse, Rat, Hamster (94%).
Target Information
H2 Histamine Receptor stimulates adenylate cyclase activity and leads to the release of acids in the stomach. It is also involved in GI motility and intestinal secretion. Treatments for acid-peptic disorders are based on the inhibition of histamine H2 receptor activity. The 3-untranslated region may be involved in differential expression. Histamine H2 receptor has been reported to be expressed in bone marrow, brain, heart, lymph node, nose, placenta, spinal cord, and stomach. An EST has been isolated from a kidney library.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: gastric receptor 1; Gastric receptor I; H2R; HH2R; Histamine H2 receptor; histamine receptor
Gene Aliases: H2R; HRH2
UniProt ID: (Human) P25021
Entrez Gene ID: (Human) 3274
histamine-induced gastric acid secretion
gastrin-induced gastric acid secretion
epithelial cell morphogenesis
immune response
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
memory
visual learning
positive regulation of vasoconstriction
regulation of synaptic plasticity
digestive tract development
gland development
toxin transport
Performance Guarantee
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