Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Recommended positive controls: mouse brain.
Predicted reactivity: Mouse (95%), Rat (97%), Zebrafish (81%), Japanese Medaka (86%), Xenopus laevis (90%), Pig (100%), Chicken (87%), Rhesus Monkey (98%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multiprotein complexes, transportation of nascent polypeptide chains across cellular membranes and regulation of protein folding. Heat shock proteins (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins and the HSP 110 family. The low molecular weight family includes HSP 10, HSP 20, HSP 27 (Heme Oxygenase 1), HSP 32 and HSP 40. Chaperonins are ubiquitous, indispensable proteins that facilitate protein folding in an ATP-dependent manner, enhancing the yield of properly folded substrate protein under conditions where spontaneous folding does not occur. Chaperonins are typified by the E. coli heat-shock proteins GroEL and GroES (HSP 10). HSP 10 is a heptameric ring of identical 10 kDa subunits that binds to each end of GroEL to form a symmetric, functional heterodimer.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 10 kDa chaperonin; 10 kDa heat shock protein, mitochondrial; 10kDa Chaperonin; CH10; Chaperonin 10; Cpn 10; CPN10; early pregnancy factor; Early-pregnancy factor; EPF; heat shock 10 kDa protein 1 (chaperonin 10); heat shock 10kD protein 1 (chaperonin 10); heat shock 10kDa protein 1; Heat shock protein family E member 1; HSP; Hsp10; mitochondrial chaperonin 10
Gene Aliases: 10kDa; CPN10; EPF; GROES; HSP10; HSPE1; mt-cpn10
UniProt ID: (Human) P61604, (Mouse) Q64433
Entrez Gene ID: (Human) 3336, (Mouse) 15528
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