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Product Details
19625-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
HYAL3 Fusion Protein Ag8611 (1-350 aa encoded by BC005896)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MTTQLGPAL VLGVALCLGC GQPLPQVPER PFSVLWNVPS AHCEARFGVH LPLNSLGIIA NRGQHFHGQN MTIFYKNQLG LYPYFGPRGT AHNGGIPQAL PLDRHLALAA YQIHHSLRPG FAGPAVLDWE EWCPLWAGNW GRRRAYQAAS WAWAQQVFPD LDPQEQLYKA YTGFEQAARA LMEDTLRVAQ ALRPHGLWGF YHYPACGNGW HSMASNYTGR CHAATLARNT QLHWLWAASS ALFPSIYLPP RLPPAHHQAF VRHRLEEAFR VALVGHRHPL PVLAYVRLTH RRSGRFLSQD DLVQSIGVSA ALGAAGVVLW GDLSLSSSEE ECWHLHDYLV DTLGPYVINV T (1-350 aa encoded by BC005896)
Target Information
This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Hyal-3; Hyaluronidase-3; Hyaluronoglucosaminidase-3; LuCa-3; LUCA14; Lung carcinoma protein 3; Minna14
Gene Aliases: HYAL-3; HYAL3; LUCA-3; LUCA3
UniProt ID: (Human) O43820
Entrez Gene ID: (Human) 8372
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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