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Invitrogen
Hepatitis B Virus Core Antigen Monoclonal Antibody (14E11)
Product Details
MA1-7610
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
14E11
Immunogen
Purified recombinant HBcAg.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Storage buffer
ascites, pH 7.2
Contains
no preservative
Storage conditions
4°C short term, -80°C long term
Shipping conditions
Dry ice
RRID
AB_1075045
Product Specific Information
MA1-7610 detects HBcAg from virus samples.
MA1-7610 has been successfully used in ELISA, WB, immunoprecipitation and immunohistochemistry procedures.
The MA1-7610 immunogen is a purified recombinant HBcAg core protein. The epitope corresponds to residues 130-140.
Target Information
The hepatitis B virus is an important cause of acute and chronic liver disease. It is also the most common form of parenterally transmitted viral hepatitis. Hepatitis B virus is spherical in shape with a diameter of 42nm. It contains a 27 nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks. The virus is estimated to affect some 350 million people worldwide. Immunization against hepatitis B is an important component of preventative medicine and is offered to all children in approximately 30 countries. Hepatitis B virus (HBV) belongs to the Hepadnaviridae family and infection with HBV is usually more serious than infection with hepatitis A virus. In some individuals the infection is not cleared and followed by persistent intracellular viral carriage that can lead to the development of hepatocelular carcinomas. There are currently 400 million HBV carriers worldwide making HBV one of the most common human pathogens.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ayw; HBc; HBcAg; HBV; HepB
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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