Proteintech

Hexokinase 1 Polyclonal Antibody

Hexokinase 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 20

Hexokinase 1 Antibody (19662-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using (Product # 19662-1-AP) (Hexokinase 1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Hexokinase 1 Antibody in Western Blot (WB)

Hexokinase 1 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

19662-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:4,000

View 26 publications 26 publications

Immunohistochemistry (IHC)

View 4 publications 4 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

View 2 publications 2 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 1 publication 1 publication

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse, Pig

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Hexokinase 1 Fusion Protein Ag8015 (583-917 aa encoded by BC008730)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: SDFLDYMGI KGPRMPLGFT FSFPCQQTSL DAGILITWTK GFKATDCVGH DVVTLLRDAI KRREEFDLDV VAVVNDTVGT MMTCAYEEPT CEVGLIVGTG SNACYMEEMK NVEMVEGDQG QMCINMEWGA FGDNGCLDDI RTHYDRLVDE YSLNAGKQRY EKMISGMYLG EIVRNILIDF TKKGFLFRGQ ISETLKTRGI FETKFLSQIE SDRLALLQVR AILQQLGLNS TCDDSILVKT VCGVVSRRAA QLCGAGMAAV VDKIRENRGL DRLNVTVGVD GTLYKLHPHF SRIMHQTVKE LSPKCNVSFL LSEDGSGKGA ALITAVGVRL RTEASS (583-917 aa encoded by BC008730)

Target Information

This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different protein isoforms have been described but their full-length nature has not been determined.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway.

International immunopharmacology

He Y,Wang Y,Jia X,Li Y,Yang Y,Pan L,Zhao R,Han Y,Wang F,Guan X,Hou T

Thu Jun 01 00:00:00 EDT 2023

Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway.

International immunopharmacology

He Y,Wang Y,Jia X,Li Y,Yang Y,Pan L,Zhao R,Han Y,Wang F,Guan X,Hou T

Thu Jun 01 00:00:00 EDT 2023

Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway.

International immunopharmacology

He Y,Wang Y,Jia X,Li Y,Yang Y,Pan L,Zhao R,Han Y,Wang F,Guan X,Hou T

Thu Jun 01 00:00:00 EDT 2023

Glycolytic reprogramming controls periodontitis-associated macrophage pyroptosis via AMPK/SIRT1/NF-κB signaling pathway.

International immunopharmacology

He Y,Wang Y,Jia X,Li Y,Yang Y,Pan L,Zhao R,Han Y,Wang F,Guan X,Hou T

Thu Jun 01 00:00:00 EDT 2023

Culture impact on the transcriptomic programs of primary and iPSC-derived human alveolar type 2 cells.

JCI insight

Alysandratos KD,Garcia-de-Alba C,Yao C,Pessina P,Huang J,Villacorta-Martin C,Hix OT,Minakin K,Burgess CL,Bawa P,Murthy A,Konda B,Beers MF,Stripp BR,Kim CF,Kotton DN

Tue Jan 10 00:00:00 EST 2023

The Effects of Prenatal Dexamethasone Exposure on Brain Metabolic Homeostasis in Adulthood: Implications for Depression.

International journal of molecular sciences

Głombik K,Kukla-Bartoszek M,Curzytek K,Detka J,Basta-Kaim A,Budziszewska B

Fri Jan 06 00:00:00 EST 2023

Magnetic Fields Reduce Apoptosis by Suppressing Phase Separation of Tau-441.

Research (Washington, D.C.)

Lin WJ,Shi WP,Ge WY,Chen LL,Guo WH,Shang P,Yin DC

Sun May 28 00:00:00 EDT 2023

Glycolytic Plasticity of Metastatic Lung Cancer Captured by Noninvasive ¹⁸F-FDG PET/CT and Serum ¹H-NMR Analysis: An Orthotopic Murine Model Study.

Metabolites

Chung YH,Hung TH,Yu CF,Tsai CK,Weng CC,Jhang F,Chen FH,Lin G

Mon Jan 09 00:00:00 EST 2023

GM3 synthase deficiency increases brain glucose metabolism in mice.

Molecular genetics and metabolism

Bharathi SS,Zhang BB,Paul E,Zhang Y,Schmidt AV,Fowler B,Wu Y,Tiemeyer M,Inamori KI,Inokuchi JI,Goetzman ES

Thu Dec 01 00:00:00 EST 2022

CYLD deficiency enhances metabolic reprogramming and tumor progression in nasopharyngeal carcinoma via PFKFB3.

Cancer letters

Wang L,Lin Y,Zhou X,Chen Y,Li X,Luo W,Zhou Y,Cai L

Thu Apr 28 00:00:00 EDT 2022

Engineering of thick human functional myocardium via static stretching and electrical stimulation.

iScience

Pretorius D,Kahn-Krell AM,LaBarge WC,Lou X,Zhang J

Fri Mar 18 00:00:00 EDT 2022

Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.

Cell biology and toxicology

Li X,Zhang Y,Wang X,Lin F,Cheng X,Wang Z,Wang X

Thu Dec 01 00:00:00 EST 2022

Long non-coding RNA CTSLP8 mediates ovarian cancer progression and chemotherapy resistance by modulating cellular glycolysis and regulating c-Myc expression through PKM2.

Cell biology and toxicology

Li X,Zhang Y,Wang X,Lin F,Cheng X,Wang Z,Wang X

Thu Dec 01 00:00:00 EST 2022

GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.

The Journal of biological chemistry

Ahat E,Bui S,Zhang J,da Veiga Leprevost F,Sharkey L,Reid W,Nesvizhskii AI,Paulson HL,Wang Y

Mon Aug 01 00:00:00 EDT 2022

Development and validation of a novel hypoxia-related signature for prognostic and immunogenic evaluation in head and neck squamous cell carcinoma.

Frontiers in oncology

Li SR,Man QW,Liu B

Fri Dec 02 00:00:00 EST 2022

NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity.

Nature immunology

Gu M,Zhou X,Sohn JH,Zhu L,Jie Z,Yang JY,Zheng X,Xie X,Yang J,Shi Y,Brightbill HD,Kim JB,Wang J,Cheng X,Sun SC

Mon Feb 01 00:00:00 EST 2021

Downregulation of GLUT3 impairs STYK1/NOK-mediated metabolic reprogramming and proliferation in NIH-3T3 cells.

Oncology letters

Shi W,Fu Y,Wang Y

Thu Jul 01 00:00:00 EDT 2021

Androgen Receptor Stimulates Hexokinase 2 and Induces Glycolysis by PKA/CREB Signaling in Hepatocellular Carcinoma.

Digestive diseases and sciences

Sun RF,Zhao CY,Chen S,Yu W,Zhou MM,Gao CR

Mon Mar 01 00:00:00 EST 2021

Targeting HLA-F suppresses the proliferation of glioma cells via a reduction in hexokinase 2-dependent glycolysis.

International journal of biological sciences

Chen X,Sun N,Li R,Sang X,Li X,Zhao J,Han J,Yang J,Ikezoe T

Thu Mar 24 00:00:00 EDT 2022

HIF-1 regulates energy metabolism of the Tibetan chicken brain during embryo development under hypoxia.

American journal of physiology. Regulatory, integrative and comparative physiology

Tang Q,Xu Q,Ding C,Zhang H,Ling Y,Wu C,Fang M

Sat May 01 00:00:00 EDT 2021

SUMOylation controls the binding of hexokinase 2 to mitochondria and protects against prostate cancer tumorigenesis.

Nature communications

Shangguan X,He J,Ma Z,Zhang W,Ji Y,Shen K,Yue Z,Li W,Xin Z,Zheng Q,Cao Y,Pan J,Dong B,Cheng J,Wang Q,Xue W

Mon Mar 22 00:00:00 EDT 2021

Mutation Promoted IL-6 Production and Glycolysis via Mediating PKM1 Stabilization in Macrophages.

Frontiers in immunology

Li R,Sun N,Chen X,Li X,Zhao J,Cheng W,Hua H,Fukatsu M,Mori H,Takahashi H,Ohkawara H,Fukami M,Okamoto M,Hamazaki Y,Zheng K,Yang J,Ikezoe T

Thu Jul 15 00:00:00 EDT 2021

Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease.

Science advances