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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
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Protein Aliases: Acetyl-Histone H2; H2A 615 antibody; H2A GL101 antibody; H2A.1 antibody; H2A/d; h2ad; H2ae; h2ai; H2ak; H2AK5ac; HIS; HIST1H2AE antibody; HIST3H2A; Histone H2A.1; Histone H2A.2; MGC74460 antibody
Gene Aliases: H2A1; H2A2; HTA1; HTA2; SPT11; YBL003C; YBL0103; YD9934.10; YDR225W
UniProt ID: (Baker's yeast) P04911, (Baker's yeast) P04912
Entrez Gene ID: (Baker's yeast) 851811, (Baker's yeast) 852283
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