Product References
Release of paused RNA polymerase II at specific loci favors DNA double-strand-break formation and promotes cancer translocations.
Nature genetics
Dellino GI,Palluzzi F,Chiariello AM,Piccioni R,Bianco S,Furia L,De Conti G,Bouwman BAM,Melloni G,Guido D,Giacò L,Luzi L,Cittaro D,Faretta M,Nicodemi M,Crosetto N,Pelicci PG
Research topic: Cancer, DNA Damage
Sat Jun 01 00:00:00 EDT 2019
Comprehensive Analysis of Chromatin States in Atypical Teratoid/Rhabdoid Tumor Identifies Diverging Roles for SWI/SNF and Polycomb in Gene Regulation.
Cancer cell
Erkek S,Johann PD,Finetti MA,Drosos Y,Chou HC,Zapatka M,Sturm D,Jones DTW,Korshunov A,Rhyzova M,Wolf S,Mallm JP,Beck K,Witt O,Kulozik AE,Frühwald MC,Northcott PA,Korbel JO,Lichter P,Eils R,Gajjar A,Roberts CWM,Williamson D,Hasselblatt M,Chavez L,Pfister SM,Kool M
Research topic: atypical teratoid rhabdoid tumors (ATRT), Gene Regulation
Mon Jan 14 00:00:00 EST 2019
RSC-Associated Subnucleosomes Define MNase-Sensitive Promoters in Yeast.
Molecular cell
Brahma S,Henikoff S
Research topic: Chromatin Structure
Thu Jan 17 00:00:00 EST 2019
Functional Landscape of PCGF Proteins Reveals Both RING1A/B-Dependent-and RING1A/B-Independent-Specific Activities.
Molecular cell
Scelfo A,Fernández-Pérez D,Tamburri S,Zanotti M,Lavarone E,Soldi M,Bonaldi T,Ferrari KJ,Pasini D
Research topic: Transcription
Thu Jun 06 00:00:00 EDT 2019
LINC00346 promotes pancreatic cancer progression through the CTCF-mediated Myc transcription.
Oncogene
Peng WX,He RZ,Zhang Z,Yang L,Mo YY
Research topic: Pancreatic cancer, pancreatic ductal adenocarcinoma (PDAC)
Tue Oct 01 00:00:00 EDT 2019
HiPLA: High-throughput imaging proximity ligation assay.
Methods (San Diego, Calif.)
Serebryannyy LA,Misteli T
Research topic: Methods Paper
Fri Mar 15 00:00:00 EDT 2019
Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure.
Alcoholism, clinical and experimental research
Jarmasz JS,Stirton H,Basalah D,Davie JR,Clarren SK,Astley SJ,Del Bigio MR
Research topic: Neurobiology, Alcoholism
Sat Jun 01 00:00:00 EDT 2019
Global DNA Methylation and Histone Posttranslational Modifications in Human and Nonhuman Primate Brain in Association with Prenatal Alcohol Exposure.
Alcoholism, clinical and experimental research
Jarmasz JS,Stirton H,Basalah D,Davie JR,Clarren SK,Astley SJ,Del Bigio MR
Research topic: Neurobiology, Alcoholism
Sat Jun 01 00:00:00 EDT 2019
IFI16, a nuclear innate immune DNA sensor, mediates epigenetic silencing of herpesvirus genomes by its association with H3K9 methyltransferases SUV39H1 and GLP.
eLife
Roy A,Ghosh A,Kumar B,Chandran B
Research topic: Virology, KSHV
Mon Nov 04 00:00:00 EST 2019
Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses.
Cancer cell
Stewart E,McEvoy J,Wang H,Chen X,Honnell V,Ocarz M,Gordon B,Dapper J,Blankenship K,Yang Y,Li Y,Shaw TI,Cho JH,Wang X,Xu B,Gupta P,Fan Y,Liu Y,Rusch M,Griffiths L,Jeon J,Freeman BB,Clay MR,Pappo A,Easton J,Shurtleff S,Shelat A,Zhou X,Boggs K,Mulder H,Yergeau D,Bahrami A,Mardis ER,Wilson RK,Zhang J,Peng J,Downing JR,Dyer MA
Research topic: Skeletal Muscle - Rhabdomyosarcoma
Mon Sep 10 00:00:00 EDT 2018
Set1 and Kdm5 are antagonists for H3K4 methylation and regulators of the major conidiation-specific transcription factor gene ABA1 in Fusarium fujikuroi.
Environmental microbiology
Janevska S,Güldener U,Sulyok M,Tudzynski B,Studt L
Research topic: Gene Regulation
Sat Sep 01 00:00:00 EDT 2018
Ascorbate Suppresses VEGF Expression in Retinal Pigment Epithelial Cells.
Investigative ophthalmology & visual science
Sant DW,Camarena V,Mustafi S,Li Y,Wilkes Z,Van Booven D,Wen R,Wang G
Research topic: Stem Cells
Mon Jul 02 00:00:00 EDT 2018
Elevated H3K79 homocysteinylation causes abnormal gene expression during neural development and subsequent neural tube defects.
Nature communications
Zhang Q,Bai B,Mei X,Wan C,Cao H,Wang S,Zhang M,Wang Z,Wu J,Wang H,Huo J,Ding G,Zhao J,Xie Q,Wang L,Qiu Z,Zhao S,Zhang T
Research topic: Brain & Nerves
Fri Aug 24 00:00:00 EDT 2018
OGT binds a conserved C-terminal domain of TET1 to regulate TET1 activity and function in development.
eLife
Hrit J,Goodrich L,Li C,Wang BA,Nie J,Cui X,Martin EA,Simental E,Fernandez J,Liu MY,Nery JR,Castanon R,Kohli RM,Tretyakova N,He C,Ecker JR,Goll M,Panning B
Research topic: Mammalian puberty & sexual development
Tue Oct 16 00:00:00 EDT 2018
Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation.
eLife
Fuentes DR,Swigut T,Wysocka J
Research topic: Gene Regulation
Thu Aug 02 00:00:00 EDT 2018
Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos.
eLife
Johnson MR,Stephenson RA,Ghaemmaghami S,Welte MA
Research topic: Gene Regulation
Wed Jul 25 00:00:00 EDT 2018
EZH2 Inhibition by Tazemetostat Results in Altered Dependency on B-cell Activation Signaling in DLBCL.
Molecular cancer therapeutics
Brach D,Johnston-Blackwell D,Drew A,Lingaraj T,Motwani V,Warholic NM,Feldman I,Plescia C,Smith JJ,Copeland RA,Keilhack H,Chan-Penebre E,Knutson SK,Ribich SA,Raimondi A,Thomenius MJ
Research topic: Lymphoma
Wed Nov 01 00:00:00 EDT 2017
Epigenetic regulation of human SOX3 gene expression during early phases of neural differentiation of NT2/D1 cells.
PloS one
Topalovic V,Krstic A,Schwirtlich M,Dolfini D,Mantovani R,Stevanovic M,Mojsin M
Research topic: Brain & Nerves
Wed Oct 18 00:00:00 EDT 2017
The Rb1 tumour suppressor gene modifies telomeric chromatin architecture by regulating TERRA expression.
Scientific reports
Gonzalez-Vasconcellos I,Schneider R,Anastasov N,Alonso-Rodriguez S,Sanli-Bonazzi B,Fernández JL,Atkinson MJ
Research topic: Osteosarcoma, Telomeres
Tue Feb 07 00:00:00 EST 2017
Regulation of endothelial intracellular adenosine via adenosine kinase epigenetically modulates vascular inflammation.
Nature communications
Xu Y,Wang Y,Yan S,Yang Q,Zhou Y,Zeng X,Liu Z,An X,Toque HA,Dong Z,Jiang X,Fulton DJ,Weintraub NL,Li Q,Bagi Z,Hong M,Boison D,Wu C,Huo Y
Research topic: Cardiovascular
Mon Oct 16 00:00:00 EDT 2017
Dynamics of RNA Polymerase II Pausing and Bivalent Histone H3 Methylation during Neuronal Differentiation in Brain Development.
Cell reports
Liu J,Wu X,Zhang H,Pfeifer GP,Lu Q
Research topic: Brain & Nerves
Tue Aug 08 00:00:00 EDT 2017
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2.
Cell research
Pan H,Guan D,Liu X,Li J,Wang L,Wu J,Zhou J,Zhang W,Ren R,Zhang W,Li Y,Yang J,Hao Y,Yuan T,Yuan G,Wang H,Ju Z,Mao Z,Li J,Qu J,Tang F,Liu GH
Research topic: Stem Cells
Mon Feb 01 00:00:00 EST 2016
LANA-Mediated Recruitment of Host Polycomb Repressive Complexes onto the KSHV Genome during De Novo Infection.
PLoS pathogens
Toth Z,Papp B,Brulois K,Choi YJ,Gao SJ,Jung JU
Research topic: HIV & AIDS
Thu Sep 01 00:00:00 EDT 2016
Anti-viral role of toll like receptor 4 in hepatitis B virus infection: An in vitro study.
World journal of gastroenterology
Das D,Sarkar N,Sengupta I,Pal A,Saha D,Bandopadhyay M,Das C,Narayan J,Singh SP,Chakravarty R
Research topic: Hepatitis B
Wed Dec 21 00:00:00 EST 2016
Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification.
F1000Research
Mendoza-Parra MA,Saravaki V,Cholley PE,Blum M,Billoré B,Gronemeyer H
Mon Jun 27 00:00:00 EDT 2016
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.
Nature
Carey BW,Finley LW,Cross JR,Allis CD,Thompson CB
Research topic: Stem Cells
Thu Feb 19 00:00:00 EST 2015
Retinoic acid is essential for Th1 cell lineage stability and prevents transition to a Th17 cell program.
Immunity
Brown CC,Esterhazy D,Sarde A,London M,Pullabhatla V,Osma-Garcia I,Al-Bader R,Ortiz C,Elgueta R,Arno M,de Rinaldis E,Mucida D,Lord GM,Noelle RJ
Research topic: Immunology & Hematology
Tue Mar 17 00:00:00 EDT 2015
NAD(+)-SIRT1 control of H3K4 trimethylation through circadian deacetylation of MLL1.
Nature structural & molecular biology
Aguilar-Arnal L,Katada S,Orozco-Solis R,Sassone-Corsi P
Research topic: Circadian Clock
Wed Apr 01 00:00:00 EDT 2015
Somatic cancer mutations in the MLL3-SET domain alter the catalytic properties of the enzyme.
Clinical epigenetics
Weirich S,Kudithipudi S,Kycia I,Jeltsch A
Research topic: Cancer
Wed Apr 01 00:00:00 EDT 2015
CXCL8 histone H3 acetylation is dysfunctional in airway smooth muscle in asthma: regulation by BET.
American journal of physiology. Lung cellular and molecular physiology
Clifford RL,Patel JK,John AE,Tatler AL,Mazengarb L,Brightling CE,Knox AJ
Research topic: Asthma
Fri May 01 00:00:00 EDT 2015
Histone methylation patterns in astrocytes are influenced by age following ischemia.
Epigenetics
Chisholm NC,Henderson ML,Selvamani A,Park MJ,Dindot S,Miranda RC,Sohrabji F
Research topic: Brain & Nerves
Mon Oct 05 00:00:00 EDT 2015
Chromatin analyses of Zymoseptoria tritici: Methods for chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).
Fungal genetics and biology : FG & B
Soyer JL,Möller M,Schotanus K,Connolly LR,Galazka JM,Freitag M,Stukenbrock EH
Research topic: Methods - ChIP in fungi
Mon Jun 01 00:00:00 EDT 2015
Chromatin analyses of Zymoseptoria tritici: Methods for chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq).
Fungal genetics and biology : FG & B
Soyer JL,Möller M,Schotanus K,Connolly LR,Galazka JM,Freitag M,Stukenbrock EH
Research topic: Methods - ChIP in fungi
Mon Jun 01 00:00:00 EDT 2015
Comparison of the cytotoxicity of cladribine and clofarabine when combined with fludarabine and busulfan in AML cells: Enhancement of cytotoxicity with epigenetic modulators.
Experimental hematology
Valdez BC,Li Y,Murray D,Ji J,Liu Y,Popat U,Champlin RE,Andersson BS
Research topic: AML
Mon Jun 01 00:00:00 EDT 2015
MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis.
PLoS genetics
Pham KT,Inoue Y,Vu BV,Nguyen HH,Nakayashiki T,Ikeda K,Nakayashiki H
Research topic: Fungus Pathogenicity
Wed Jul 01 00:00:00 EDT 2015
MoSET1 (Histone H3K4 Methyltransferase in Magnaporthe oryzae) Regulates Global Gene Expression during Infection-Related Morphogenesis.
PLoS genetics
Pham KT,Inoue Y,Vu BV,Nguyen HH,Nakayashiki T,Ikeda K,Nakayashiki H
Research topic: Fungus Pathogenicity
Wed Jul 01 00:00:00 EDT 2015
Histone modifications change with age, dietary restriction and rapamycin treatment in mouse brain.
Oncotarget
Gong H,Qian H,Ertl R,Astle CM,Wang GG,Harrison DE,Xu X
Research topic: Neurodegeneration, Alzheimers, Parkinson, Huntington
Tue Jun 30 00:00:00 EDT 2015
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia.
Nature
Ntziachristos P,Tsirigos A,Welstead GG,Trimarchi T,Bakogianni S,Xu L,Loizou E,Holmfeldt L,Strikoudis A,King B,Mullenders J,Becksfort J,Nedjic J,Paietta E,Tallman MS,Rowe JM,Tonon G,Satoh T,Kruidenier L,Prinjha R,Akira S,Van Vlierberghe P,Ferrando AA,Jaenisch R,Mullighan CG,Aifantis I
Research topic: Leukemia
Thu Oct 23 00:00:00 EDT 2014
An epigenomic approach to therapy for tamoxifen-resistant breast cancer.
Cell research
Feng Q,Zhang Z,Shea MJ,Creighton CJ,Coarfa C,Hilsenbeck SG,Lanz R,He B,Wang L,Fu X,Nardone A,Song Y,Bradner J,Mitsiades N,Mitsiades CS,Osborne CK,Schiff R,O'Malley BW
Research topic: Breast Cancer
Tue Jul 01 00:00:00 EDT 2014
Vascular histone deacetylation by pharmacological HDAC inhibition.
Genome research
Rafehi H,Balcerczyk A,Lunke S,Kaspi A,Ziemann M,Kn H,Okabe J,Khurana I,Ooi J,Khan AW,Du XJ,Chang L,Haviv I,Keating ST,Karagiannis TC,El-Osta A
Research topic: Cardiovascular
Fri Aug 01 00:00:00 EDT 2014
In situ histone landscape of nephrogenesis.
Epigenetics
McLaughlin N,Wang F,Saifudeen Z,El-Dahr SS
Research topic: Nephrogenesis
Sat Feb 01 00:00:00 EST 2014
Chromatin and transcription transitions of mammalian adult germline stem cells and spermatogenesis.
Cell stem cell
Hammoud SS,Low DH,Yi C,Carrell DT,Guccione E,Cairns BR
Research topic: Spermatogenesis, Stem Cells
Thu Aug 07 00:00:00 EDT 2014
Epigenetic coordination of signaling pathways during the epithelial-mesenchymal transition.
Epigenetics & chromatin
Cieślik M,Hoang SA,Baranova N,Chodaparambil S,Kumar M,Allison DF,Xu X,Wamsley JJ,Gray L,Jones DR,Mayo MW,Bekiranov S
Research topic: Chromatin Remodeling
Mon Sep 02 00:00:00 EDT 2013
Microenvironment promotes tumor cell reprogramming in human breast cancer cell lines.
PloS one
D'Anselmi F,Masiello MG,Cucina A,Proietti S,Dinicola S,Pasqualato A,Ricci G,Dobrowolny G,Catizone A,Palombo A,Bizzarri M
Research topic: Breast Cancer
Sun Aug 31 00:00:00 EDT 2014
Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest.
Cell stem cell
Rada-Iglesias A,Bajpai R,Prescott S,Brugmann SA,Swigut T,Wysocka J
Research topic: Neurobiology, Developmental Biology
Fri Nov 02 00:00:00 EDT 2012
Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/β-catenin target gene expression.
Nucleic acids research
Wallmen B,Schrempp M,Hecht A
Mon Oct 01 00:00:00 EDT 2012
BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression.
PLoS pathogens
Woellmer A,Arteaga-Salas JM,Hammerschmidt W
Research topic: Transcription Regulation
Sat Sep 01 00:00:00 EDT 2012
Masculine epigenetic sex marks of the CYP19A1/aromatase promoter in genetically male chicken embryonic gonads are resistant to estrogen-induced phenotypic sex conversion.
Biology of reproduction
Ellis HL,Shioda K,Rosenthal NF,Coser KR,Shioda T
Research topic: Embryonic Sex Differentiation
Sun Jul 01 00:00:00 EDT 2012
Synergistic cytotoxicity of the DNA alkylating agent busulfan, nucleoside analogs and suberoylanilide hydroxamic acid in lymphoma cell lines.
Leukemia & lymphoma
Valdez BC,Murray D,Nieto Y,Li Y,Wang G,Champlin RE,Andersson BS
Research topic: Cancer, Lymphoma
Tue May 01 00:00:00 EDT 2012
Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions.
Cell
Ruthenburg AJ,Li H,Milne TA,Dewell S,McGinty RK,Yuen M,Ueberheide B,Dou Y,Muir TW,Patel DJ,Allis CD
Research topic: Chromatin Structure
Fri May 27 00:00:00 EDT 2011
Global and gene-specific histone modification profiles of mouse multipotent adult germline stem cells.
Molecular human reproduction
Khromov T,Pantakani DV,Nolte J,Wolf M,Dressel R,Engel W,Zechner U
Research topic: Stem Cells
Tue Mar 01 00:00:00 EST 2011
NF-Y recruits Ash2L to impart H3K4 trimethylation on CCAAT promoters.
PloS one
Fossati A,Dolfini D,Donati G,Mantovani R
Research topic: Transcription Regulation
Mon Mar 21 00:00:00 EDT 2011
