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Human IgG4 Antibody (MA5-49495) in IHC (P)
Immunohistochemistry analysis of Human IgG4 formalin-fixed paraffin-embedded human tonsil tissue. Samples were incubated in Human IgG4 Monoclonal Antibody (14H8) (Product # MA5-49495) using a dilution of 1 µg/mL at room temperature for 1 hour followed by poly-peroxidase conjugated goat anti-mouse IgG was used as the secondary antibody. Antigen was retrieved through addition of boiling Tris/EDTA buffer pH 9 ... View More
Product Details
MA5-49495
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
14H8
Immunogen
Recombinant Human IgG4
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_3090656
Product Specific Information
This product was used in an Indirect ELISA.
This product does not cross-react with human IgG1, IgG2, IgG3, IgA, IgM and IgE.
Target Information
Human IgG4, also known as human immunoglobulin G4, is a subclass of human IgG antibodies that is produced by the immune system in response to antigens. It is the least abundant subclass of IgG in the blood and plays a minor role in defense against pathogens. IgG4 works by binding to specific antigens and promoting their clearance from the body through various mechanisms, including phagocytosis and complement activation. IgG4 is also involved in other immune responses, such as immune tolerance and suppression of inflammation. Human IgG4 can be used in research to study the immune response to pathogens and to develop diagnostic tests and therapeutic interventions for infectious and autoimmune diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Immunoglobulin G; Immunoglobulin G4; ImmunoglobulinG
Entrez Gene ID: (Human) 3503
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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