Product References
The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria.
Cell reports
Bassot A,Chen J,Takahashi-Yamashiro K,Yap MC,Gibhardt CS,Le GNT,Hario S,Nasu Y,Moore J,Gutiérrez T,Mina L,Mast H,Moses A,Bhat R,Ballanyi K,Lemieux H,Sitia R,Zito E,Bogeski I,Campbell RE,Simmen T
Tue Jan 31 00:00:00 EST 2023
Sirt3-dependent regulation of mitochondrial oxidative stress and apoptosis contributes to the dysfunction of pancreatic islets after severe burns.
Free radical biology & medicine
Liu X,Xie X,Li D,Liu Z,Zhang B,Zang Y,Yuan H,Shen C
Wed Mar 01 00:00:00 EST 2023
Astaxanthin promotes mitochondrial biogenesis and antioxidant capacity in chronic high-intensity interval training.
European journal of nutrition
Wang Y,Chen X,Baker JS,Davison GW,Xu S,Zhou Y,Bao X
Sat Apr 01 00:00:00 EDT 2023
Changes in the Expression of MIF and Other Key Enzymes of Energy Metabolism in the Myocardia of Broiler Chickens with Ascites Syndrome.
Animals : an open access journal from MDPI
Li L,Jia Q,Chen L,Wang W
Tue Sep 20 00:00:00 EDT 2022
Non-oxidative pentose phosphate pathway controls regulatory T cell function by integrating metabolism and epigenetics.
Nature metabolism
Liu Q,Zhu F,Liu X,Lu Y,Yao K,Tian N,Tong L,Figge DA,Wang X,Han Y,Li Y,Zhu Y,Hu L,Ji Y,Xu N,Li D,Gu X,Liang R,Gan G,Wu L,Zhang P,Xu T,Hu H,Hu Z,Xu H,Ye D,Yang H,Li B,Tong X
Sun May 01 00:00:00 EDT 2022
The mTOR/PGC-1α/SIRT3 Pathway Drives Reductive Glutamine Metabolism to Reduce Oxidative Stress Caused by ISKNV in CPB Cells.
Microbiology spectrum
Fu X,Li K,Niu Y,Lin Q,Liang H,Luo X,Liu L,Li N
Wed Feb 23 00:00:00 EST 2022
Dietary Salt Disrupts Tricarboxylic Acid Cycle and Induces Tau Hyperphosphorylation and Synapse Dysfunction during Aging.
Aging and disease
Yuan M,Wang Y,Wen J,Jing F,Zou Q,Pu Y,Pan T,Cai Z
Sat Oct 01 00:00:00 EDT 2022
Polarization and β-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues.
Journal of immunology (Baltimore, Md. : 1950)
Fan TW,Daneshmandi S,Cassel TA,Uddin MB,Sledziona J,Thompson PT,Lin P,Higashi RM,Lane AN
Tue Nov 01 00:00:00 EDT 2022
Comparison of viral RNA-host protein interactomes across pathogenic RNA viruses informs rapid antiviral drug discovery for SARS-CoV-2.
Cell research
Zhang S,Huang W,Ren L,Ju X,Gong M,Rao J,Sun L,Li P,Ding Q,Wang J,Zhang QC
Sat Jan 01 00:00:00 EST 2022
MUC1 triggers lineage plasticity of Her2 positive mammary tumors.
Oncogene
Pang Z,Dong X,Deng H,Wang C,Liao X,Liao C,Liao Y,Tian W,Cheng J,Chen G,Yi H,Huang L
Sun May 01 00:00:00 EDT 2022
MUC1 triggers lineage plasticity of Her2 positive mammary tumors.
Oncogene
Pang Z,Dong X,Deng H,Wang C,Liao X,Liao C,Liao Y,Tian W,Cheng J,Chen G,Yi H,Huang L
Sun May 01 00:00:00 EDT 2022
MUC1 triggers lineage plasticity of Her2 positive mammary tumors.
Oncogene
Pang Z,Dong X,Deng H,Wang C,Liao X,Liao C,Liao Y,Tian W,Cheng J,Chen G,Yi H,Huang L
Sun May 01 00:00:00 EDT 2022
MUC1 triggers lineage plasticity of Her2 positive mammary tumors.
Oncogene
Pang Z,Dong X,Deng H,Wang C,Liao X,Liao C,Liao Y,Tian W,Cheng J,Chen G,Yi H,Huang L
Sun May 01 00:00:00 EDT 2022
Global profiling of protein lysine malonylation in mouse cardiac hypertrophy.
Journal of proteomics
Wu LF,Wang DP,Shen J,Gao LJ,Zhou Y,Liu QH,Cao JM
Tue Aug 30 00:00:00 EDT 2022
SIRT5 alleviates hepatic ischemia and reperfusion injury by diminishing oxidative stress and inflammation via elevating SOD1 and IDH2 expression.
Experimental cell research
Zheng D,He D,He Y,Yang J
Sat Oct 15 00:00:00 EDT 2022
Therapeutic targeting of glutamate dehydrogenase 1 that links metabolic reprogramming and Snail-mediated epithelial-mesenchymal transition in drug-resistant lung cancer.
Pharmacological research
Wang Q,Wu M,Li H,Rao X,Ao L,Wang H,Yao L,Wang X,Hong X,Wang J,Aa J,Sun M,Wang G,Liu J,Zhou F
Tue Nov 01 00:00:00 EDT 2022
Cryptotanshinone suppresses tumorigenesis by inhibiting lipogenesis and promoting reactive oxygen species production in KRAS‑activated pancreatic cancer cells.
International journal of oncology
Terado T,Kim CJ,Ushio A,Minami K,Tambe Y,Kageyama S,Kawauchi A,Tsunoda T,Shirasawa S,Tanaka H,Inoue H
Thu Sep 01 00:00:00 EDT 2022
Mandarin Fish (Siniperca chuatsi) p53 Regulates Glutaminolysis Induced by Virus via the p53/miR145-5p/c-Myc Pathway in Chinese Perch Brain Cells.
Microbiology spectrum
Ye C,Liu S,Li N,Zuo S,Niu Y,Lin Q,Liang H,Luo X,Fu X
Wed Apr 27 00:00:00 EDT 2022
Sodium cantharidate induces Apoptosis in breast cancer cells by regulating energy metabolism via the protein phosphatase 5-p53 axis.
Toxicology and applied pharmacology
Pang JL,Huang FH,Zhang YH,Wu Y,Ge XM,Li S,Li X
Mon Nov 01 00:00:00 EDT 2021
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
American journal of physiology. Cell physiology
Peoples JN,Ghazal N,Duong DM,Hardin KR,Manning JR,Seyfried NT,Faundez V,Kwong JQ
Wed Sep 01 00:00:00 EDT 2021
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
American journal of physiology. Cell physiology
Peoples JN,Ghazal N,Duong DM,Hardin KR,Manning JR,Seyfried NT,Faundez V,Kwong JQ
Wed Sep 01 00:00:00 EDT 2021
Mild Hypothermia Attenuates Hepatic Ischemia-Reperfusion Injury through Regulating the JAK2/STAT3-CPT1a-Dependent Fatty Acid β-Oxidation.
Oxidative medicine and cellular longevity
Wang W,Hu X,Xia Z,Liu Z,Zhong Z,Lu Z,Liu A,Ye S,Cao Q,Wang Y,Zhu F,Ye Q
Wed Dec 16 00:00:00 EST 2020
STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Molecular systems biology
Oberhuber M,Pecoraro M,Rusz M,Oberhuber G,Wieselberg M,Haslinger P,Gurnhofer E,Schlederer M,Limberger T,Lagger S,Pencik J,Kodajova P,Högler S,Stockmaier G,Grund-Gröschke S,Aberger F,Bolis M,Theurillat JP,Wiebringhaus R,Weiss T,Haitel A,Brehme M,Wadsak W,Griss J,Mohr T,Hofer A,Jäger A,Pollheimer J,Egger G,Koellensperger G,Mann M,Hantusch B,Kenner L
Wed Apr 01 00:00:00 EDT 2020
STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Molecular systems biology
Oberhuber M,Pecoraro M,Rusz M,Oberhuber G,Wieselberg M,Haslinger P,Gurnhofer E,Schlederer M,Limberger T,Lagger S,Pencik J,Kodajova P,Högler S,Stockmaier G,Grund-Gröschke S,Aberger F,Bolis M,Theurillat JP,Wiebringhaus R,Weiss T,Haitel A,Brehme M,Wadsak W,Griss J,Mohr T,Hofer A,Jäger A,Pollheimer J,Egger G,Koellensperger G,Mann M,Hantusch B,Kenner L
Wed Apr 01 00:00:00 EDT 2020
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
British journal of cancer
Chen X,Zhuo S,Xu W,Chen X,Huang D,Sun X,Cheng Y
Wed Jul 01 00:00:00 EDT 2020
Isocitrate dehydrogenase 2 contributes to radiation resistance of oesophageal squamous cell carcinoma via regulating mitochondrial function and ROS/pAKT signalling.
British journal of cancer
Chen X,Zhuo S,Xu W,Chen X,Huang D,Sun X,Cheng Y
Wed Jul 01 00:00:00 EDT 2020
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Cell reports
Bott AJ,Shen J,Tonelli C,Zhan L,Sivaram N,Jiang YP,Yu X,Bhatt V,Chiles E,Zhong H,Maimouni S,Dai W,Velasquez S,Pan JA,Muthalagu N,Morton J,Anthony TG,Feng H,Lamers WH,Murphy DJ,Guo JY,Jin J,Crawford HC,Zhang L,White E,Lin RZ,Su X,Tuveson DA,Zong WX
Tue Oct 29 00:00:00 EDT 2019
Two human patient mitochondrial pyruvate carrier mutations reveal distinct molecular mechanisms of dysfunction.
JCI insight
Oonthonpan L,Rauckhorst AJ,Gray LR,Boutron AC,Taylor EB
Thu May 30 00:00:00 EDT 2019
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 EDT 2018
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 EDT 2018
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Journal of ethnopharmacology
Wu L,Cao KX,Ni ZH,Li WD,Chen ZP,Cheng HB,Liu X
Fri Aug 10 00:00:00 EDT 2018
Effects of Dahuang zhechong pill on doxorubicin-resistant SMMC-7721 xenografts in mice.
Journal of ethnopharmacology
Wu L,Cao KX,Ni ZH,Li WD,Chen ZP,Cheng HB,Liu X
Fri Aug 10 00:00:00 EDT 2018
Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.
Scientific reports
White K,Kim MJ,Han C,Park HJ,Ding D,Boyd K,Walker L,Linser P,Meneses Z,Slade C,Hirst J,Santostefano K,Terada N,Miyakawa T,Tanokura M,Salvi R,Someya S
Thu Mar 22 00:00:00 EDT 2018
Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.
Scientific reports
White K,Kim MJ,Han C,Park HJ,Ding D,Boyd K,Walker L,Linser P,Meneses Z,Slade C,Hirst J,Santostefano K,Terada N,Miyakawa T,Tanokura M,Salvi R,Someya S
Thu Mar 22 00:00:00 EDT 2018
Metabolic Mechanisms and a Rational Combinational Application of Carboxyamidotriazole in Fighting Pancreatic Cancer Progression after Chemotherapy.
The Journal of pharmacology and experimental therapeutics
Ju R,Fei K,Li S,Chen C,Zhu L,Li J,Zhang D,Guo L,Ye C
Mon Oct 01 00:00:00 EDT 2018
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
EMBO reports
Zhong X,Tian S,Zhang X,Diao X,Dong F,Yang J,Li Z,Sun L,Wang L,He X,Wu G,Hu X,Wang L,Song L,Zhang H,Pan X,Li A,Gao P
Mon May 01 00:00:00 EDT 2017
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
EMBO reports
Zhong X,Tian S,Zhang X,Diao X,Dong F,Yang J,Li Z,Sun L,Wang L,He X,Wu G,Hu X,Wang L,Song L,Zhang H,Pan X,Li A,Gao P
Mon May 01 00:00:00 EDT 2017
Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.
Antioxidants & redox signaling
Liu G,Park SH,Imbesi M,Nathan WJ,Zou X,Zhu Y,Jiang H,Parisiadou L,Gius D
Sat May 20 00:00:00 EDT 2017
Loss of NAD-Dependent Protein Deacetylase Sirtuin-2 Alters Mitochondrial Protein Acetylation and Dysregulates Mitophagy.
Antioxidants & redox signaling
Liu G,Park SH,Imbesi M,Nathan WJ,Zou X,Zhu Y,Jiang H,Parisiadou L,Gius D
Sat May 20 00:00:00 EDT 2017
The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma.
American journal of cancer research
Chen X,Xu W,Wang C,Liu F,Guan S,Sun Y,Wang X,An D,Wen Z,Chen P,Cheng Y
Wed Sep 30 00:00:00 EDT 2020
The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma.
American journal of cancer research
Chen X,Xu W,Wang C,Liu F,Guan S,Sun Y,Wang X,An D,Wen Z,Chen P,Cheng Y
Wed Sep 30 00:00:00 EDT 2020
The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma.
American journal of cancer research
Chen X,Xu W,Wang C,Liu F,Guan S,Sun Y,Wang X,An D,Wen Z,Chen P,Cheng Y
Wed Sep 30 00:00:00 EDT 2020
The clinical significance of isocitrate dehydrogenase 2 in esophageal squamous cell carcinoma.
American journal of cancer research
Chen X,Xu W,Wang C,Liu F,Guan S,Sun Y,Wang X,An D,Wen Z,Chen P,Cheng Y
Wed Sep 30 00:00:00 EDT 2020
Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1.
Oncology reports
Zang S,Tang Q,Dong F,Liu H,Li L,Guo F,Pan X,Lin H,Zeng W,Cai Z,Zhong Q,Zang N,Zang L
Fri Dec 01 00:00:00 EST 2017
Curcumol inhibits the proliferation of gastric adenocarcinoma MGC-803 cells via downregulation of IDH1.
Oncology reports
Zang S,Tang Q,Dong F,Liu H,Li L,Guo F,Pan X,Lin H,Zeng W,Cai Z,Zhong Q,Zang N,Zang L
Fri Dec 01 00:00:00 EST 2017
SIRT3-Mediated Dimerization of IDH2 Directs Cancer Cell Metabolism and Tumor Growth.
Cancer research
Zou X,Zhu Y,Park SH,Liu G,O'Brien J,Jiang H,Gius D
Tue Aug 01 00:00:00 EDT 2017
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Scientific reports
Li P,Zhang D,Shen L,Dong K,Wu M,Ou Z,Shi D
Wed Mar 09 00:00:00 EST 2016
Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells.
Scientific reports
Li P,Zhang D,Shen L,Dong K,Wu M,Ou Z,Shi D
Wed Mar 09 00:00:00 EST 2016
On the Utility of Short Echo Time (TE) Single Voxel 1H-MRS in Non-Invasive Detection of 2-Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel.
PloS one
Heo H,Kim S,Lee HH,Cho HR,Xu WJ,Lee SH,Park CK,Park S,Choi SH,Kim H
Wed Jul 06 00:00:00 EDT 2016
On the Utility of Short Echo Time (TE) Single Voxel 1H-MRS in Non-Invasive Detection of 2-Hydroxyglutarate (2HG); Challenges and Potential Improvement Illustrated with Animal Models Using MRUI and LCModel.
PloS one
Heo H,Kim S,Lee HH,Cho HR,Xu WJ,Lee SH,Park CK,Park S,Choi SH,Kim H
Wed Jul 06 00:00:00 EDT 2016
Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
Journal of neurochemistry
Wen H,Cho HR,Yun T,Kim H,Park CK,Lee SH,Choi SH,Park S
Thu Jan 01 00:00:00 EST 2015
Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
Journal of neurochemistry
Wen H,Cho HR,Yun T,Kim H,Park CK,Lee SH,Choi SH,Park S
Thu Jan 01 00:00:00 EST 2015
Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
Journal of neurochemistry
Wen H,Cho HR,Yun T,Kim H,Park CK,Lee SH,Choi SH,Park S
Thu Jan 01 00:00:00 EST 2015
Metabolomic comparison between cells over-expressing isocitrate dehydrogenase 1 and 2 mutants and the effects of an inhibitor on the metabolism.
Journal of neurochemistry
Wen H,Cho HR,Yun T,Kim H,Park CK,Lee SH,Choi SH,Park S
Thu Jan 01 00:00:00 EST 2015
MiR-181a regulates lipid metabolism via IDH1.
Scientific reports
Chu B,Wu T,Miao L,Mei Y,Wu M
Thu Mar 05 00:00:00 EST 2015
MiR-181a regulates lipid metabolism via IDH1.
Scientific reports
Chu B,Wu T,Miao L,Mei Y,Wu M
Thu Mar 05 00:00:00 EST 2015
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Nature communications
Ma X,Li C,Sun L,Huang D,Li T,He X,Wu G,Yang Z,Zhong X,Song L,Gao P,Zhang H
Fri Oct 10 00:00:00 EDT 2014
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Nature communications
Ma X,Li C,Sun L,Huang D,Li T,He X,Wu G,Yang Z,Zhong X,Song L,Gao P,Zhang H
Fri Oct 10 00:00:00 EDT 2014
Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs.
American journal of physiology. Lung cellular and molecular physiology
Agarwal AR,Zhao L,Sancheti H,Sundar IK,Rahman I,Cadenas E
Thu Nov 15 00:00:00 EST 2012
Short-term cigarette smoke exposure induces reversible changes in energy metabolism and cellular redox status independent of inflammatory responses in mouse lungs.
American journal of physiology. Lung cellular and molecular physiology
Agarwal AR,Zhao L,Sancheti H,Sundar IK,Rahman I,Cadenas E
Thu Nov 15 00:00:00 EST 2012