Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
IFITM1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 8
IFITM1 Antibody (PA5-92168) in IHC (P)
Immunohistochemistry analysis of IFITM1 in paraffin-embedded mouse kidney. Samples were incubated with IFITM1 Polyclonal antibody (Product # PA5-92168) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-92168
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-125 of human CD225/IFITM1 (NP_0036323)
Conjugate
Form
Liquid
Concentration
2.26 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806398
Product Specific Information
Immunogen sequence: CCLGFIAFAY SVKSRDRKMV GDVTGAQAYA STAKCLNIWA LILGILMTIG FILLLVFGSV TVYHIMLQII QEKRGY; Positive Samples: K-562; Cellular Location: Cell membrane, Single-pass membrane protein
Target Information
IFITM1 (Interferon inducible transmembrane protein 1) is a member of the IFN-inducible transmembrane protein family. It is an essential mediator of interferon-gamma-induced antiproliferation and plays a role in the control of cell growth. IFITM1 is upregulated in several tumor types and may be useful as a tumor biomarker. Both mouse IFITM1 and IFITM3 are expressed on the cell surfaces of primordial germ cells in a developmentally-regulated manner. IFITM1 activity is required for primordial germ cell transit, and IFITM1 acts as a repulsive molecule by repelling non-IFITM1-expressing primordial germ cells from the mesoderm into the endoderm.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: 27-Sep; CD225; Dispanin subfamily A member 2a; DSPA2a; Fragilis protein 2; fragilis2; ifitm-like protein 2; interferon induced transmembrane protein 2 like; Interferon-induced protein 17; Interferon-induced transmembrane protein 1; Interferon-inducible protein 9-27; Leu-13 antigen; Mil-2; Mouse ifitm-like protein 2
Gene Aliases: 1110036C17Rik; 9-27; CD225; DSPA2a; IFI17; IFITM1; LEU13; Mil-2; Mil2
UniProt ID: (Human) P13164, (Mouse) Q9D103
Entrez Gene ID: (Human) 8519, (Mouse) 68713
ossification
cell surface receptor signaling pathway
negative regulation of cell proliferation
response to virus
negative regulation of cell migration
response to interferon-gamma
response to interferon-alpha
response to interferon-beta
negative regulation of viral genome replication
positive regulation of osteoblast differentiation
negative regulation of viral entry into host cell
regulation of immune response
defense response to virus
type I interferon signaling pathway
somitogenesis
immune system process
response to biotic stimulus
anterior/posterior pattern specification
innate immune response
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support